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Mrpl37 Gene Detail
Summary
  • Symbol
    Mrpl37
  • Name
    mitochondrial ribosomal protein L37
  • Synonyms
    2300004O14Rik, MRP-L2, Rpml2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926268
    NCBI Gene: 56280
  • Gene Overview
    MyGene.info: MRPL37
Location & Maps
more
  • Sequence Map
    Chr4:107055874-107066868 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10995 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 49.99 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MRPL37, mitochondrial ribosomal protein L37
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRPL37, mitochondrial ribosomal protein L37
    Orthology source: HomoloGene, HGNC
  • Synonyms
    L2mt, L37mt, MRPL2, MRP-L2, MRP-L37, RPML2
  • Links
    NCBI Gene ID: 51253
    neXtProt AC: NX_Q9BZE1

  • Chr Location
    1p32.3; chr1:54200167-54226682 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9536
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MRPL37
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Mrpl37
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008412 VEGA Gene Model | MGI Sequence Detail 10995 C57BL/6J ±  kb
transcript OTTMUST00000019087 VEGA | MGI Sequence Detail 1498 Not Applicable  
polypeptide OTTMUSP00000008749 VEGA | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    63 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 125
    cDNA 125

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913592, MGI:2140198
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:64919 Graack HR, et al., Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle. Biochemistry. 1999 Dec 14;38(50):16569-77
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory