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Tspan6 Gene Detail
Summary
  • Symbol
    Tspan6
  • Name
    tetraspanin 6
  • Synonyms
    6720473L21Rik, Tm4sf6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926264
    NCBI Gene: 56496
  • Gene Overview
    MyGene.info: TSPAN6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:133891068-133898429 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 55.47 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926264
protein coding gene ChrX:133891068-133898429 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036057
protein coding gene ChrX:131036241-131043605 (-)
A/J MGP_AJ_G0036039
protein coding gene ChrX:130463374-130471297 (-)
AKR/J MGP_AKRJ_G0035958
protein coding gene ChrX:134631133-134638494 (-)
BALB/cJ MGP_BALBcJ_G0036030
protein coding gene ChrX:128912858-128920214 (-)
C3H/HeJ MGP_C3HHeJ_G0035734
protein coding gene ChrX:131118845-131126205 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036552
protein coding gene ChrX:134902275-134909635 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033380
protein coding gene ChrX:122671451-122678805 (-)
CAST/EiJ MGP_CASTEiJ_G0035021
protein coding gene ChrX:111997655-112005005 (-)
CBA/J MGP_CBAJ_G0035711
protein coding gene ChrX:138935816-138943518 (-)
DBA/2J MGP_DBA2J_G0035864
protein coding gene ChrX:129805003-129812367 (-)
FVB/NJ MGP_FVBNJ_G0035806
protein coding gene ChrX:129116350-129123721 (-)
LP/J MGP_LPJ_G0035957
protein coding gene ChrX:131914353-131921705 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035834
protein coding gene ChrX:146336573-146343930 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036581
protein coding gene ChrX:130464200-130471532 (-)
PWK/PhJ MGP_PWKPhJ_G0034713
protein coding gene ChrX:108950997-108958351 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034545
protein coding gene ChrX:112621796-112629177 (-)
WSB/EiJ MGP_WSBEiJ_G0035158
protein coding gene ChrX:128849209-128856591 (-)



Homology
more
  • Human Ortholog
    TSPAN6, tetraspanin 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TSPAN6, tetraspanin 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    T245, TM4SF6, TSPAN-6
  • Links
    NCBI Gene ID: 7105
    neXtProt AC: NX_O43657
    UniProt: O43657

  • Chr Location
    Xq22.1; chrX:100627108-100637104 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56496 NCBI Gene Model | MGI Sequence Detail 7362 C57BL/6J ±  kb
transcript NM_019656 RefSeq | MGI Sequence Detail 1763 C57BL/6  
polypeptide O70401 UniProt | EBI | MGI Sequence Detail 245 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 63
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1924400, MGI:2147866
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:64920 Todd SC, et al., Sequences and expression of six new members of the tetraspanin/TM4SF family. Biochim Biophys Acta. 1998 Jul 30;1399(1):101-4
  • Latest
    J:201159 Zhou P, et al., Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15395-400

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory