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Gbp3 Gene Detail
Summary
  • Symbol
    Gbp3
  • Name
    guanylate binding protein 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926263
    NCBI Gene: 55932
Location & Maps
more
  • Sequence Map
    Chr3:142560026-142573209 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13184 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 66.69 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GBP4, guanylate binding protein 4
  • Vertebrate Orthologs
    5
  • Human Ortholog
    GBP4, guanylate binding protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Mpa2
  • Links
    NCBI Gene ID: 115361
    neXtProt AC: NX_Q96PP9

  • Chr Location
    1p22.2; chr1:89181148-89198950 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Gbp3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023133 VEGA Gene Model | MGI Sequence Detail 13184 C57BL/6J ±  kb
transcript OTTMUST00000055907 VEGA | MGI Sequence Detail 2629 Not Applicable  
polypeptide OTTMUSP00000026819 VEGA | MGI Sequence Detail 620 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    298 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domain
    IPR003191 Guanylate-binding protein, C-terminal
    IPR015894 Guanylate-binding protein, N-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 62
    cDNA 62

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139979
References
more
  • Summaries
    All 25
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:48603 Han BH, et al., Cloning, expression, and characterization of a novel guanylate-binding protein, GBP3 in murine erythroid progenitor cells. Biochim Biophys Acta. 1998 May 19;1384(2):373-86
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory