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Dexi Gene Detail
Summary
  • Symbol
    Dexi
  • Name
    dexamethasone-induced transcript
  • Synonyms
    1810029J14Rik, D16Bwg0586e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926236
    NCBI Gene: 58239
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10530207-10543054 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 5.67 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926236
 protein coding gene Chr16:10502531-10543054 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022509
 protein coding gene Chr16:7308576-7351217 (-)
A/J MGP_AJ_G0022471
 protein coding gene Chr16:6905369-6950683 (-)
AKR/J MGP_AKRJ_G0022447
 protein coding gene Chr16:7229751-7270152 (-)
BALB/cJ MGP_BALBcJ_G0022475
 protein coding gene Chr16:7040937-7083452 (-)
C3H/HeJ MGP_C3HHeJ_G0022242
 protein coding gene Chr16:7305221-7346486 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022924
 protein coding gene Chr16:7458588-7502848 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020445
 protein coding gene Chr16:7050809-7092093 (-)
CAST/EiJ MGP_CASTEiJ_G0021769
 protein coding gene Chr16:7321562-7365292 (-)
CBA/J MGP_CBAJ_G0022211
 protein coding gene Chr16:7785072-7829022 (-)
DBA/2J MGP_DBA2J_G0022342
 protein coding gene Chr16:6916293-6956988 (-)
FVB/NJ MGP_FVBNJ_G0022318
 protein coding gene Chr16:6898322-6940178 (-)
LP/J MGP_LPJ_G0022410
 protein coding gene Chr16:7266145-7309712 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022340
 protein coding gene Chr16:7523891-7567435 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022937
 protein coding gene Chr16:7174224-7217198 (-)
PWK/PhJ MGP_PWKPhJ_G0021509
 protein coding gene Chr16:7119596-7161441 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021339
 protein coding gene Chr16:7240484-7281543 (-)
WSB/EiJ MGP_WSBEiJ_G0021817
 protein coding gene Chr16:7250333-7292607 (-)



Homology
more
  • Human Ortholog
    DEXI, Dexi homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DEXI, Dexi homolog
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MYLE
  • Links
    NCBI Gene ID: 28955
    neXtProt AC: NX_O95424
    UniProt: O95424

  • Chr Location
    16p13.13; chr16:10928891-10943007 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 8517
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DEXI
  • Gene Tree
    Dexi
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal response to poly I:C and susceptibility to diabetes.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    632
  • Tissues
    1
  • cDNA Data
    33
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 58239 NCBI Gene Model | MGI Sequence Detail 12848 C57BL/6J ±  kb
transcript NM_021428 RefSeq | MGI Sequence Detail 1394 C57BL/6  
polypeptide Q9WUQ7 UniProt | EBI | MGI Sequence Detail 95 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 34
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33992, MGI:106300, MGI:1916391, MGI:2146487, MGI:2146637
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Phenotypes 4
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:285312 Nieves-Bonilla JM, et al., The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model. Genes Immun. 2020 Jan;21(1):71-77
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/23/2021
MGI 6.16 		The Jackson Laboratory