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Stx6 Gene Detail
Summary
  • Symbol
    Stx6
  • Name
    syntaxin 6
  • Synonyms
    2310039E05Rik, 2410005I16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926235
    NCBI Gene: 58244
  • Gene Overview
    MyGene.info: STX6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:155158677-155207567 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 66.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    355 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926235
protein coding gene Chr1:155158677-155208256 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016611
protein coding gene Chr1:160062791-160116704 (+)
A/J MGP_AJ_G0016592
protein coding gene Chr1:153639262-153688599 (+)
AKR/J MGP_AKRJ_G0016558
protein coding gene Chr1:158363031-158417422 (+)
BALB/cJ MGP_BALBcJ_G0016553
protein coding gene Chr1:154151308-154201442 (+)
C3H/HeJ MGP_C3HHeJ_G0016377
protein coding gene Chr1:158491501-158542552 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017014
protein coding gene Chr1:165576104-165629397 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014723
protein coding gene Chr1:145866554-145917364 (+)
CAST/EiJ MGP_CASTEiJ_G0015957
protein coding gene Chr1:158009310-158063742 (+)
CBA/J MGP_CBAJ_G0016352
protein coding gene Chr1:171423651-171475858 (+)
DBA/2J MGP_DBA2J_G0016458
protein coding gene Chr1:152618082-152668467 (+)
FVB/NJ MGP_FVBNJ_G0016456
protein coding gene Chr1:151084590-151137071 (+)
LP/J MGP_LPJ_G0016529
protein coding gene Chr1:161216961-161272669 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016481
protein coding gene Chr1:178999419-179057683 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017050
protein coding gene Chr1:158170383-158221252 (+)
PWK/PhJ MGP_PWKPhJ_G0015743
protein coding gene Chr1:151685448-151736950 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015530
protein coding gene Chr1:156912850-156968079 (+)
WSB/EiJ MGP_WSBEiJ_G0016019
protein coding gene Chr1:158237010-158288784 (+)



Homology
more
  • Human Ortholog
    STX6, syntaxin 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STX6, syntaxin 6
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10228
    neXtProt AC: NX_O43752
    UniProt: O43752

  • Chr Location
    1q25.3; chr1:180949690-181023121 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 58244 NCBI Gene Model | MGI Sequence Detail 48891 C57BL/6J ±  kb
transcript NM_021433 RefSeq | MGI Sequence Detail 2459 C57BL/6  
polypeptide Q9JKK1 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 7
Other
Accession IDs
less
MGI:1915516, MGI:1916870, MGI:2138226, MGI:2138343, MGI:3035316
References
more
  • Summaries
    All 47
    Developmental Gene Expression 4
    Gene Ontology 19
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:253982 Norlin S, et al., The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory