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Stx6
Gene Detail
Symbol

Name
ID
Stx6
syntaxin 6
MGI:1926235
Synonyms
2310039E05Rik, 2410005I16Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
66.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:155158703-155203517 bp, + strand
From NCBI annotation of GRCm38

  44815 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115622  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: syntaxin10/6
Gene Tree: Stx6

Human
homologs
Human Homolog STX6, syntaxin 6
NCBI Gene ID 10228
neXtProt AC  NX_O43752
Human Chr (Location)  1q25.3; chr1:180972712-181023121 (-)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Stx6 interacts with 215 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process endosome organization, Golgi vesicle transport, ...
Component early endosome, Golgi apparatus, ...
Function protein binding, SNAP receptor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000026470 (Evidence)
Entrez Gene58244 (Evidence)
DFCITC1572812, TC1593833, TC1645230, TC1704198
NIA Mouse Gene IndexU000939
Consensus CDS ProjectCCDS35741.1
International Mouse Knockout Project StatusStx6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 58244 NCBI Gene Model | MGI Sequence Detail 44815 C57BL/6J ±  kb
transcript NM_021433 RefSeq | MGI Sequence Detail 2459 C57BL/6 
polypeptide Q9JKK1 UniProt | EBI | MGI Sequence Detail 255 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(329 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015260 Syntaxin 6, N-terminal
InterPro IPR006012 Syntaxin/epimorphin, conserved site
InterPro IPR000727 Target SNARE coiled-coil domain
InterPro IPR010989 t-SNARE
Protein Ontology PR:000015798 syntaxin-6
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201362 Morawski M, et al., Cellular and ultra structural evidence for cytoskeletal localization of prolyl endopeptidase-like protein in neurons. Neuroscience. 2013 Jul 9;242:128-39
All references(42)
Other
accession IDs
MGI:1915516, MGI:1916870, MGI:2138226, MGI:2138343, MGI:3035316

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory