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Fibp Gene Detail
Summary
  • Symbol
    Fibp
  • Name
    fibroblast growth factor (acidic) intracellular binding protein
  • Synonyms
    2010004G08Rik, 2010005N21Rik, 3010027N18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926233
    NCBI Gene: 58249
  • Gene Overview
    MyGene.info: FIBP
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5460616-5465051 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.33 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926233
protein coding gene Chr19:5460600-5465052 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024708
protein coding gene Chr19:2429845-2434294 (+)
A/J MGP_AJ_G0024674
protein coding gene Chr19:2295255-2299702 (+)
AKR/J MGP_AKRJ_G0024647
protein coding gene Chr19:2353164-2357612 (+)
BALB/cJ MGP_BALBcJ_G0024674
protein coding gene Chr19:2289009-2293457 (+)
C3H/HeJ MGP_C3HHeJ_G0024442
protein coding gene Chr19:2362728-2367175 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025121
protein coding gene Chr19:2485436-2489886 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022551
protein coding gene Chr19:2197614-2202308 (+)
CAST/EiJ MGP_CASTEiJ_G0023914
protein coding gene Chr19:2390190-2394618 (+)
CBA/J MGP_CBAJ_G0024414
protein coding gene Chr19:2594829-2599280 (+)
DBA/2J MGP_DBA2J_G0024541
protein coding gene Chr19:2274634-2279087 (+)
FVB/NJ MGP_FVBNJ_G0024508
protein coding gene Chr19:2281409-2285858 (+)
LP/J MGP_LPJ_G0024627
protein coding gene Chr19:2409309-2413759 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024538
protein coding gene Chr19:2449505-2453945 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025169
protein coding gene Chr19:2370982-2375432 (+)
PWK/PhJ MGP_PWKPhJ_G0023660
protein coding gene Chr19:2311662-2316168 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023465
protein coding gene Chr19:2355737-2360096 (+)
WSB/EiJ MGP_WSBEiJ_G0023976
protein coding gene Chr19:2381895-2386350 (+)



Homology
more
  • Human Ortholog
    FIBP, FGF1 intracellular binding protein
  • Vertebrate Orthologs
    11
  • Human Ortholog
    FIBP, FGF1 intracellular binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FGFIBP, FIBP-1, TROFAS
  • Links
    NCBI Gene ID: 9158
    neXtProt AC: NX_O43427
    UniProt: O43427

  • Chr Location
    11q13.1; chr11:65883740-65888539 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3106
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;3 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FIBP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024911 Ensembl Gene Model | MGI Sequence Detail 4436 C57BL/6J ±  kb
transcript ENSMUST00000025847 Ensembl | MGI Sequence Detail 1215 Not Applicable  
polypeptide ENSMUSP00000025847 Ensembl | MGI Sequence Detail 364 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR008614 Acidic fibroblast growth factor intracellular-binding protein
Molecular
Reagents
less
  • All nucleic 72
    cDNA 72

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913680, MGI:1924201, MGI:1924334
References
more
  • Summaries
    All 25
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:66718 Kolpakova E, et al., Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein. Biochem J. 2000 Dec 15;352 Pt 3:629-35
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory