About   Help   FAQ
Rnase4
Gene Detail
Symbol

Name
ID
Rnase4
ribonuclease, RNase A family 4
MGI:1926217
Synonyms
C730049F20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
26.37 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:51091077-51106151 bp, + strand
From NCBI annotation of GRCm38

  15075 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10576  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog

HCOP human homology predictions: RNASE4
Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase4

Human
homologs
RNASE4, ribonuclease, RNase A family, 4
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6038
neXtProt AC: NX_P34096

Human Synonyms: RAB1, RNS4

Human Chr (Location): 14q11; chr14:20684213-20700602 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Rnase4 interacts with 127 markers (Mir1a-1, Mir1a-2, Mir17, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (66)    Tissues (7)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 66
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000021876 (Evidence)
Entrez Gene 58809 (Evidence)
DFCI TC1576645
DoTS DT.101709262, DT.537084
EC 3.1.27.-
Consensus CDS Project CCDS27035.1
International Mouse Phenotyping Consortium Status Rnase4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 58809 NCBI Gene Model | MGI Sequence Detail 15075 C57BL/6J ±  kb
transcript NM_201239 RefSeq | MGI Sequence Detail 1837 C57BL/6 
polypeptide Q9JJH1 UniProt | EBI | MGI Sequence Detail 148 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(278 from dbSNP Build 137)    SNPs within 2kb including multiple locations(298)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023411 Ribonuclease A, active site
InterPro IPR023412 Ribonuclease A-domain
Protein Ontology PR:000014048 ribonuclease 4
Graphical View of Protein Domain Structure
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(27)
Other
accession IDs
MGI:2442584

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory