About   Help   FAQ
Rnase4
Gene Detail
Symbol

Name
ID
Rnase4
ribonuclease, RNase A family 4
MGI:1926217
Synonyms
C730049F20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
26.37 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:51091077-51106151 bp, + strand
From NCBI annotation of GRCm38

  15075 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10576  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase4

Human
homologs
Human Homolog RNASE4, ribonuclease, RNase A family, 4
NCBI Gene ID 6038
neXtProt AC  NX_P34096
Human Synonyms  RAB1, RNS4
Human Chr (Location)  14q11; chr14:20684213-20700602 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rnase4 interacts with 127 markers (Mir1a-1, Mir1a-2, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process cellular response to starvation
Component extracellular region, extracellular vesicular exosome
Function endonuclease activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (66)    Tissues (7)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 66
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000021876 (Evidence)
Entrez Gene58809 (Evidence)
DFCITC1576645
DoTSDT.537084, DT.101709262
EC3.1.27.-
Consensus CDS ProjectCCDS27035.1
International Mouse Knockout Project StatusRnase4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 58809 NCBI Gene Model | MGI Sequence Detail 15075 C57BL/6J ±  kb
transcript NM_201239 RefSeq | MGI Sequence Detail 1837 C57BL/6 
polypeptide Q9JJH1 UniProt | EBI | MGI Sequence Detail 148 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(4) UniProt(9)
Polymorphisms
SNPs within 2kb(278 from dbSNP Build 137)    SNPs within 2kb including multiple locations(298)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023411 Ribonuclease A, active site
InterPro IPR023412 Ribonuclease A-domain
Protein Ontology PR:000014048 ribonuclease 4
Graphical View of Protein Domain Structure
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(28)
Other
accession IDs
MGI:2442584

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory