Rnase4
Gene Detail

Symbol Name ID

Rnase4 ribonuclease, RNase A family 4 MGI:1926217

Synonyms

C730049F20Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 14

26.37 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr14:51091077-51106151 bp, + strand From NCBI annotation of GRCm38   15075 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10576  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase4

Human homologs

Human Homolog		RNASE4, ribonuclease, RNase A family, 4
NCBI Gene ID		6038
neXtProt AC		NX_P34096
Human Synonyms		RNS4
Human Chr (Location)		14q11; chr14:21152372-21168758 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(1) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	biological_process
Component	extracellular region
Function	endonuclease activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (66)    Tissues (7)    Images (25)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	66

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(5)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000021876 (Evidence)
Entrez Gene	58809 (Evidence)
DFCI	TC1576645
DoTS	DT.101709262, DT.537084
EC	3.1.27.-
Consensus CDS Project	CCDS27035.1
International Mouse Knockout Project Status	Rnase4

Sequences

Length	Strain/Species
genomic	58809	NCBI Gene Model | MGI Sequence Detail	15075	C57BL/6J
transcript	NM_201239	RefSeq | MGI Sequence Detail	1837	C57BL/6
polypeptide	Q9JJH1	UniProt | EBI | MGI Sequence Detail	148	Not Applicable

All sequences(27) RefSeq(4) UniProt(5)

Polymorphisms

SNPs(147 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001427	Ribonuclease A
InterPro	IPR023411	Ribonuclease A, active site
InterPro	IPR023412	Ribonuclease A-domain
Protein Ontology	PR:000014048	ribonuclease 4

Graphical View of Protein Domain Structure

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(28)

Other accession IDs

MGI:2442584