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Dek
Gene Detail
Symbol

Name
ID
Dek
DEK oncogene (DNA binding)
MGI:1926209
Synonyms
1810019E15Rik, D13H6S231E
Feature Type
protein coding gene
Genetic Map
Chromosome 13
24.50 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr13:47084775-47106201 bp, - strand
From VEGA annotation of GRCm38

  21427 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2593  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: DEK
Gene Tree: Dek

Human
homologs
DEK, DEK proto-oncogene
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 7913
neXtProt AC: NX_P35659

Human Synonyms: D6S231E

Human Chr (Location): 6p22.3; chr6:18224169-18264568 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(45) : Gene trapped(41) Targeted(4)
Incidental mutations (data from Mutagenetix )
 
Mice homozygous for a null allele exhibit delayed development of DMBA- and TPA-induced papillomas.
 
Interactions
Dek interacts with 259 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell quiescence, chromatin modification, ...
Component contractile fiber, nucleus
Function DNA binding, histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (24)    Tissues (19)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 8
RT-PCR 16
cDNA source data(226)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dek ; ZFIN dek    NEW 
Molecular
reagents
All nucleic(229) cDNA(227) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000024779 (Evidence)
Ensembl Gene Model ENSMUSG00000021377 (Evidence)
Entrez Gene 110052 (Evidence)
UniGene 131150
DFCI TC1572283
NIA Mouse Gene Index U034741
Consensus CDS Project CCDS26490.1
International Mouse Phenotyping Consortium Status Dek
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024779 VEGA Gene Model | MGI Sequence Detail 21427 C57BL/6J ±  kb
transcript OTTMUST00000061016 VEGA | MGI Sequence Detail 2556 Not Applicable 
polypeptide OTTMUSP00000029851 VEGA | MGI Sequence Detail 380 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(3) UniProt(6)
Polymorphisms
RFLP(1) : SNPs within 2kb(126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014876 DEK, C-terminal
InterPro IPR009057 Homeodomain-like
InterPro IPR003034 SAP domain
Protein Ontology PR:000006415 protein DEK
References
(Earliest) J:14384 Copeland NG, et al., A genetic linkage map of the mouse: current applications and future prospects [see comments]. Science. 1993 Oct 1;262(5130):57-66
(Latest) J:181629 Cheung TH, et al., Maintenance of muscle stem-cell quiescence by microRNA-489. Nature. 2012 Feb 23;482(7386):524-8
All references(48)
Other
accession IDs
MGD-MRK-3410, MGI:1914254, MGI:89627

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory