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Stap1 Gene Detail
Summary
  • Symbol
    Stap1
  • Name
    signal transducing adaptor family member 1
  • Synonyms
    Brdg1, STAP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926193
    NCBI Gene: 56792
  • Gene Overview
    MyGene.info: STAP1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:86071746-86106125 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 43.56 cM, cytoband E1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    187 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926193
protein coding gene Chr5:86071584-86106125 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029664
protein coding gene Chr5:86897908-86935331 (+)
A/J MGP_AJ_G0029632
protein coding gene Chr5:83343215-83376592 (+)
AKR/J MGP_AKRJ_G0029580
protein coding gene Chr5:86110185-86143951 (+)
BALB/cJ MGP_BALBcJ_G0029641
protein coding gene Chr5:84251743-84284853 (+)
C3H/HeJ MGP_C3HHeJ_G0029364
protein coding gene Chr5:86601320-86635627 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030095
protein coding gene Chr5:90480667-90519320 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027337
protein coding gene Chr5:79209922-79246137 (+)
CAST/EiJ MGP_CASTEiJ_G0028772
protein coding gene Chr5:85854885-85894328 (+)
CBA/J MGP_CBAJ_G0029333
protein coding gene Chr5:93377076-93419162 (+)
DBA/2J MGP_DBA2J_G0029478
protein coding gene Chr5:83518961-83551275 (+)
FVB/NJ MGP_FVBNJ_G0029439
protein coding gene Chr5:82477247-82510869 (+)
LP/J MGP_LPJ_G0029565
protein coding gene Chr5:87306243-87338963 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029467
protein coding gene Chr5:98184884-98231365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030128
protein coding gene Chr5:85695590-85733773 (+)
PWK/PhJ MGP_PWKPhJ_G0028496
protein coding gene Chr5:82503350-82537162 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028330
protein coding gene Chr5:85050051-85081850 (+)
WSB/EiJ MGP_WSBEiJ_G0028853
protein coding gene Chr5:86035906-86070428 (+)



Homology
more
  • Human Ortholog
    STAP1, signal transducing adaptor family member 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STAP1, signal transducing adaptor family member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BRDG1, STAP-1
  • Links
    NCBI Gene ID: 26228
    neXtProt AC: NX_Q9ULZ2
    UniProt: Q9ULZ2

  • Chr Location
    4q13.2; chr4:67558697-67607341 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8103
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: STAP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029254 Ensembl Gene Model | MGI Sequence Detail 34380 C57BL/6J ±  kb
transcript ENSMUST00000198435 Ensembl | MGI Sequence Detail 3350 Not Applicable  
polypeptide ENSMUSP00000143251 Ensembl | MGI Sequence Detail 297 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140935
References
more
  • Summaries
    All 37
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:190322 Archambaud C, et al., Impact of lactobacilli on orally acquired listeriosis. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16684-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory