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Stap1 Gene Detail
Summary
  • Symbol
    Stap1
  • Name
    signal transducing adaptor family member 1
  • Synonyms
    Brdg1, STAP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926193
    NCBI Gene: 56792
  • Gene Overview
    MyGene.info: STAP1
Location & Maps
more
  • Sequence Map
    Chr5:86071746-86106125 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34380 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    STAP1, signal transducing adaptor family member 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STAP1, signal transducing adaptor family member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BRDG1, STAP-1
  • Links
    NCBI Gene ID: 26228
    neXtProt AC: NX_Q9ULZ2

  • Chr Location
    4q13.2; chr4:67558728-67607337 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Stap1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022745 VEGA Gene Model | MGI Sequence Detail 34380 C57BL/6J ±  kb
transcript OTTMUST00000054587 VEGA | MGI Sequence Detail 3350 Not Applicable  
polypeptide OTTMUSP00000026072 VEGA | MGI Sequence Detail 297 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    187 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140935
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:64951 Masuhara M, et al., Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains. Biochem Biophys Res Commun. 2000 Feb 24;268(3):697-703
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory