Stap1
Gene Detail

Symbol Name ID

Stap1 signal transducing adaptor family member 1 MGI:1926193

Synonyms

Brdg1, STAP-1

Feature Type

protein coding gene

Genetic Map

Chromosome 5

43.56 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr5:86071746-86103993 bp, + strand From VEGA annotation of GRCm38   32248 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8103  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Stap1

Human homologs

Human Homolog		STAP1, signal transducing adaptor family member 1
NCBI Gene ID		26228
neXtProt AC		NX_Q9ULZ2
Human Synonyms		BRDG1, STAP-1
Human Chr (Location)		4q13.2; chr4:68424446-68472616 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	myeloid cell differentiation, transmembrane receptor protein tyrosine kinase signaling pathway
Component	cytoplasm, intracellular membrane-bounded organelle, ...
Function	phospholipid binding, protein binding, ...

External Resources: FuncBase

Expression

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(12)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000022745 (Evidence)
Ensembl Gene Model	ENSMUSG00000029254 (Evidence)
Entrez Gene	56792 (Evidence)
UniGene	131237
DFCI	TC1586434, TC1593195
DoTS	DT.40170714, DT.87070274, DT.91563321
NIA Mouse Gene Index	U005734
Consensus CDS Project	CCDS19377.1
International Mouse Knockout Project Status	Stap1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022745	VEGA Gene Model | MGI Sequence Detail	32248	C57BL/6J
transcript	OTTMUST00000054587	VEGA | MGI Sequence Detail	1218	Not Applicable
polypeptide	OTTMUSP00000026072	VEGA | MGI Sequence Detail	297	Not Applicable

All sequences(34) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(130 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001849	Pleckstrin homology domain
InterPro	IPR011993	Pleckstrin homology-like domain
InterPro	IPR000980	SH2 domain
Protein Ontology	PR:000015713	signal-transducing adaptor protein 1

References

(Earliest) J:64951 Masuhara M, et al., Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains. Biochem Biophys Res Commun. 2000 Feb 24;268(3):697-703
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGI:2140935