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Pigt Gene Detail
Summary
  • Symbol
    Pigt
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class T
  • Synonyms
    2510012P17Rik, 4930534E15Rik, CGI-06, NDAP, Ndap7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926178
    NCBI Gene: 78928
  • Gene Overview
    MyGene.info: PIGT
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164497520-164508301 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.17 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926178
protein coding gene Chr2:164497510-164508301 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026856
protein coding gene Chr2:169946124-169958227 (+)
A/J MGP_AJ_G0026822
protein coding gene Chr2:163027082-163037618 (+)
AKR/J MGP_AKRJ_G0026793
protein coding gene Chr2:167867486-167880269 (+)
BALB/cJ MGP_BALBcJ_G0026831
protein coding gene Chr2:163388895-163399898 (+)
C3H/HeJ MGP_C3HHeJ_G0026573
protein coding gene Chr2:168223060-168233637 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027279
protein coding gene Chr2:174872107-174888720 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024649
protein coding gene Chr2:156436531-156446891 (+)
CAST/EiJ MGP_CASTEiJ_G0026033
protein coding gene Chr2:168645115-168656926 (+)
CBA/J MGP_CBAJ_G0026550
protein coding gene Chr2:181216517-181227285 (+)
DBA/2J MGP_DBA2J_G0026688
protein coding gene Chr2:162197421-162207990 (+)
FVB/NJ MGP_FVBNJ_G0026654
protein coding gene Chr2:160612400-160623514 (+)
LP/J MGP_LPJ_G0026791
protein coding gene Chr2:170027176-170037770 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026674
protein coding gene Chr2:184803539-184817025 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027335
protein coding gene Chr2:167769695-167780279 (+)
PWK/PhJ MGP_PWKPhJ_G0025768
protein coding gene Chr2:161775831-161787152 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025571
protein coding gene Chr2:166641763-166653948 (+)
WSB/EiJ MGP_WSBEiJ_G0026104
protein coding gene Chr2:168637746-168648279 (+)



Homology
more
  • Human Ortholog
    PIGT, phosphatidylinositol glycan anchor biosynthesis class T
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PIGT, phosphatidylinositol glycan anchor biosynthesis class T
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-06, MCAHS3, NDAP, PNH2
  • Links
    NCBI Gene ID: 51604
    neXtProt AC: NX_Q969N2
    UniProt: Q969N2

  • Chr Location
    20q13.12; chr20:45416067-45426245 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human PIGT associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation do not survive.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017721 Ensembl Gene Model | MGI Sequence Detail 10782 C57BL/6J ±  kb
transcript ENSMUST00000103101 Ensembl | MGI Sequence Detail 2562 Not Applicable  
polypeptide ENSMUSP00000099390 Ensembl | MGI Sequence Detail 582 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919706
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory