About   Help   FAQ
Pigt Gene Detail
Summary
  • Symbol
    Pigt
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class T
  • Synonyms
    2510012P17Rik, 4930534E15Rik, CGI-06, NDAP, Ndap7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926178
    NCBI Gene: 78928
  • Gene Overview
    MyGene.info: PIGT
Location & Maps
more
  • Sequence Map
    Chr2:164497520-164508301 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10782 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.17 cM, cytoband H3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PIGT, phosphatidylinositol glycan anchor biosynthesis class T
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PIGT, phosphatidylinositol glycan anchor biosynthesis class T
    Orthology source: HomoloGene
  • Synonyms
    CGI-06, MCAHS3, NDAP, PNH2
  • Links
    NCBI Gene ID: 51604
    neXtProt AC: NX_Q969N2

  • Chr Location
    20q13.12; chr20:45416067-45426245 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human PIGT associations

Human Disease Mouse Models
       Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome 3; MCAHS3   OMIM: 615398
Paroxysmal Nocturnal Hemoglobinuria 2; PNH2   OMIM: 615399
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Targeted
    3
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001092 VEGA Gene Model | MGI Sequence Detail 10782 C57BL/6J ±  kb
transcript OTTMUST00000002147 VEGA | MGI Sequence Detail 2562 Not Applicable  
polypeptide OTTMUSP00000001046 VEGA | MGI Sequence Detail 582 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    121 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000012707 GPI transamidase component PIG-T
  • InterPro Domains
    IPR007245 GPI transamidase component PIG-T
Molecular
Reagents
less
  • All nucleic 69
    cDNA 69

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919706
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory