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Fndc8 Gene Detail
Summary
  • Symbol
    Fndc8
  • Name
    fibronectin type III domain containing 8
  • Synonyms
    4930466G16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926169
    NCBI Gene: 78919
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:82782971-82791563 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 50.30 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926169
protein coding gene Chr11:82782950-82791627 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018833
protein coding gene Chr11:84174952-84189854 (+)
A/J MGP_AJ_G0018800
protein coding gene Chr11:80940916-80950271 (+)
AKR/J MGP_AKRJ_G0018770
protein coding gene Chr11:83367690-83381103 (+)
BALB/cJ MGP_BALBcJ_G0018773
protein coding gene Chr11:81344882-81353994 (+)
C3H/HeJ MGP_C3HHeJ_G0018587
protein coding gene Chr11:83402721-83411274 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019225
protein coding gene Chr11:86696595-86707960 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016859
protein coding gene Chr11:77904719-77913516 (+)
CAST/EiJ MGP_CASTEiJ_G0018142
protein coding gene Chr11:83991057-84000768 (+)
CBA/J MGP_CBAJ_G0018558
protein coding gene Chr11:90451511-90461650 (+)
DBA/2J MGP_DBA2J_G0018666
protein coding gene Chr11:80516078-80524927 (+)
FVB/NJ MGP_FVBNJ_G0018655
protein coding gene Chr11:80041329-80050351 (+)
LP/J MGP_LPJ_G0018736
protein coding gene Chr11:84689975-84699551 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018682
protein coding gene Chr11:90648629-90658117 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019265
protein coding gene Chr11:83630270-83640182 (+)
PWK/PhJ MGP_PWKPhJ_G0017912
protein coding gene Chr11:81337308-81346543 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017703
protein coding gene Chr11:83253329-83262047 (+)
WSB/EiJ MGP_WSBEiJ_G0018194
protein coding gene Chr11:83516456-83526773 (+)



Homology
more
  • Human Ortholog
    FNDC8, fibronectin type III domain containing 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FNDC8, fibronectin type III domain containing 8
  • Links
    NCBI Gene ID: 54752
    neXtProt AC: NX_Q8TC99
    UniProt: Q8TC99

  • Chr Location
    17q12; chr17:35121612-35130732 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Male mice homozygous for a null allele exhibit normal fecundity.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78919 NCBI Gene Model | MGI Sequence Detail 8593 C57BL/6J ±  kb
transcript NM_030224 RefSeq | MGI Sequence Detail 2081 Not Specified  
polypeptide Q9D2H8 UniProt | EBI | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory