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Mdn1
Gene Detail
Symbol

Name
ID
Mdn1
midasin homolog (yeast)
MGI:1926159
Synonyms
4833432B22Rik, D4Abb1e, LOC213784
Feature Type
protein coding gene
Genetic Map
Chromosome 4
14.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr4:32657119-32775207 bp, + strand
From VEGA annotation of GRCm38

  118089 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39689  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MDN1
Protein SuperFamily: midasin
Gene Tree: Mdn1

Human
homologs
MDN1, midasin AAA ATPase 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23195
neXtProt AC: NX_Q9NU22

Human Synonyms: Rea1

Human Chr (Location): 6q15; chr6:89642775-89827961 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Gene trapped(27) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Mdn1 interacts with 342 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biological_process
Component cytoplasm, intermediate filament cytoskeleton, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(122)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mdn1 ; ZFIN mdn1    NEW 
Molecular
reagents
All nucleic(124) cDNA(123) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000004945 (Evidence)
Ensembl Gene Model ENSMUSG00000058006 (Evidence)
Entrez Gene 100019 (Evidence)
UniGene 24627
DFCI TC1579575, TC1593600, TC1590126, TC1593459, TC1715016, TC1606419, TC1630111
DoTS DT.101366610, DT.101225196, DT.101371477, DT.97414426, DT.97347893, DT.110824238, DT.40180683
NIA Mouse Gene Index U042515
Consensus CDS Project CCDS57264.1
International Mouse Phenotyping Consortium Status Mdn1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004945 VEGA Gene Model | MGI Sequence Detail 118089 C57BL/6J ±  kb
transcript OTTMUST00000011001 VEGA | MGI Sequence Detail 17970 Not Applicable 
polypeptide OTTMUSP00000005134 VEGA | MGI Sequence Detail 5589 Not Applicable 

For the selected sequences
All sequences(75) RefSeq(7) UniProt(7)
Polymorphisms
SNPs within 2kb(612 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR011704 ATPase, dynein-related, AAA domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR002035 von Willebrand factor, type A
Protein Ontology PR:000010269 midasin
References
(Earliest) J:34960 Chambers DM, et al., Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains. Genome Res. 1996 Aug;6(8):715-23
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)
Other
accession IDs
MGD-MRK-33917, MGI:106225, MGI:2140177, MGI:2684981

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory