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Wrnip1
Gene Detail
Symbol

Name
ID
Wrnip1
Werner helicase interacting protein 1
MGI:1926153
Synonyms
4833444L21Rik, WHIP
Feature Type
protein coding gene
Genetic Map
Chromosome 13
13.74 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:32802038-32822609 bp, + strand
From VEGA annotation of GRCm38

  20572 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10592  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Wrnip1

Human
homologs
Human Homolog WRNIP1, Werner helicase interacting protein 1
NCBI Gene ID 56897
neXtProt AC  NX_Q96S55
Human Synonyms  bA420G6.2, WHIP
Human Chr (Location)  6p25.2; chr6:2765341-2785745 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(5) Radiation induced(1) Targeted(4)
Genomic Mutations involving Wrnip1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Wrnip1 interacts with 139 markers (Mir16-1, Mir16-2, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process ATP catabolic process, cellular response to DNA damage stimulus, ...
Component membrane, nucleus, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (57)    Tissues (31)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 57
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) Genomic(3) cDNA(12)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000000693 (Evidence)
Ensembl Gene ModelENSMUSG00000021400 (Evidence)
Entrez Gene78903 (Evidence)
DFCITC1574708
DoTSDT.101331928, DT.101311767
EC3.6.1.3
Consensus CDS ProjectCCDS26427.1
International Mouse Knockout Project StatusWrnip1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000693 VEGA Gene Model | MGI Sequence Detail 20572 C57BL/6J ±  kb
transcript OTTMUST00000001325 VEGA | MGI Sequence Detail 2633 Not Applicable 
polypeptide OTTMUSP00000000622 VEGA | MGI Sequence Detail 660 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR003959 ATPase, AAA-type, core
InterPro IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
InterPro IPR021886 MgsA AAA+ ATPase C-terminal
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR006642 Zinc finger, Rad18-type putative
Protein Ontology PR:000017456 ATPase WRNIP1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory