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Pus7l
Gene Detail
Symbol

Name
ID
Pus7l
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
MGI:1926145
Synonyms
3000003F02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
48.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:94522688-94543547 bp, - strand
From VEGA annotation of GRCm38

  20860 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12842  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: pseudouridine synthase, eukaryotic type
Gene Tree: Pus7l

Human
homologs
Human Homolog PUS7L, pseudouridylate synthase 7 homolog (S. cerevisiae)-like
NCBI Gene ID 83448
neXtProt AC  NX_Q9H0K6
Human Chr (Location)  12q12; chr12:43728025-43758817 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Pus7l (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pus7l interacts with 95 markers (Mir18, Mir18b, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process pseudouridine synthesis, RNA modification, ...
Component cellular_component
Function baruol synthase activity, beta-amyrin synthase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (3)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 5
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023451 (Evidence)
Ensembl Gene ModelENSMUSG00000033356 (Evidence)
Entrez Gene78895 (Evidence)
UniGene34344
DFCITC1595435, TC1581635
DoTSDT.101185451, DT.94258040, DT.102530839, DT.94258045
NIA Mouse Gene IndexU036574
EC5.4.99.-
Consensus CDS ProjectCCDS27771.1
International Mouse Knockout Project StatusPus7l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023451 VEGA Gene Model | MGI Sequence Detail 20860 C57BL/6J ±  kb
transcript OTTMUST00000057018 VEGA | MGI Sequence Detail 2840 Not Applicable 
polypeptide OTTMUSP00000027461 VEGA | MGI Sequence Detail 702 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(192 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020103 Pseudouridine synthase, catalytic domain
InterPro IPR001656 Pseudouridine synthase, TruD
InterPro IPR017091 Pseudouridine synthase TruD, eukaryotic
InterPro IPR011760 Pseudouridine synthase, TruD, insertion domain
Protein Ontology PR:000013500 pseudouridylate synthase 7-like protein
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory