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Wsb1 Gene Detail
Summary
  • Symbol
    Wsb1
  • Name
    WD repeat and SOCS box-containing 1
  • Synonyms
    1110056B13Rik, 2700038M07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926139
    NCBI Gene: 78889
  • Gene Overview
    MyGene.info: WSB1
Location & Maps
more
  • Sequence Map
    Chr11:79239372-79254671 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15300 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    WSB1, WD repeat and SOCS box containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WSB1, WD repeat and SOCS box containing 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SWIP1, WSB-1
  • Links
    NCBI Gene ID: 26118
    neXtProt AC: NX_Q9Y6I7

  • Chr Location
    17q11.1; chr17:27294080-27313844 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9218
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: WSB1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    2 involving Wsb1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000167 VEGA Gene Model | MGI Sequence Detail 15300 C57BL/6J ±  kb
transcript OTTMUST00000000511 VEGA | MGI Sequence Detail 2476 Not Applicable  
polypeptide OTTMUSP00000000225 VEGA | MGI Sequence Detail 421 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    85 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923579
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 15
  • Earliest
    J:51029 Hilton DJ, et al., Twenty proteins containing a C-terminal SOCS box form five structural classes. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):114-9
  • Latest
    J:220398 Werneck de Castro JP, et al., Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine. J Clin Invest. 2015 Feb;125(2):769-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory