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Sfi1 Gene Detail
Summary
  • Symbol
    Sfi1
  • Name
    Sfi1 homolog, spindle assembly associated (yeast)
  • Synonyms
    2310047I15Rik, mKIAA0542
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926137
    NCBI Gene: 78887
  • Gene Overview
    MyGene.info: SFI1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3131850-3193463 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 2.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    659 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926137
protein coding gene Chr11:3131850-3203346 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017951
protein coding gene Chr11:519-32535 (-)
A/J MGP_AJ_G0017924
protein coding gene Chr11:5894-100929 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0017892
protein coding gene Chr11:19982-75908 (-)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0016004
protein coding gene Chr11:13911-21417 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0017680
protein coding gene Chr11:87163-91882 (-)
DBA/2J MGP_DBA2J_G0017791
protein coding gene Chr11:8387-23905 (-)
FVB/NJ MGP_FVBNJ_G0029210
protein coding gene Chr5:29420761-29440709 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0016843
protein coding gene Chr11:915-60485 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SFI1, SFI1 centrin binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SFI1, SFI1 centrin binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hSfi1p, PISD, PPP1R139
  • Links
    NCBI Gene ID: 9814
    neXtProt AC: NX_A8K8P3
    UniProt: A8K8P3

  • Chr Location
    22q12.2; chr22:31496139-31618554 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12707
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SFI1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023764 Ensembl Gene Model | MGI Sequence Detail 61614 C57BL/6J ±  kb
transcript ENSMUST00000081318 Ensembl | MGI Sequence Detail 3969 Not Applicable  
polypeptide ENSMUSP00000080066 Ensembl | MGI Sequence Detail 1216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory