About   Help   FAQ
Rhot1
Gene Detail
Symbol

Name
ID
Rhot1
ras homolog gene family, member T1
MGI:1926078
Synonyms
2210403N23Rik, Arht1, C430039G08Rik, FLJ11040, Miro1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
47.62 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:80209019-80267486 bp, + strand
From VEGA annotation of GRCm38

  58468 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56803  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: RHOT1
Protein SuperFamily: mitochondrial Rho GTPase
Gene Tree: Rhot1

Human
homologs
RHOT1, ras homolog family member T1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55288
neXtProt AC: NX_Q8IXI2

Human Synonyms: ARHT1, MIRO1, MIRO-1

Human Chr (Location): 17q11.2; chr17:32142454-32253374 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(80) : Gene trapped(75) Targeted(5)
Genomic Mutations involving Rhot1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rhot1 interacts with 340 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(27)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rhot1 ; ZFIN rhot1a    NEW 
Molecular
reagents
All nucleic(27) cDNA(27)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000000219 (Evidence)
Ensembl Gene Model ENSMUSG00000017686 (Evidence)
Entrez Gene 59040 (Evidence)
DFCI TC1619324, TC1665061, TC1608669, TC1607121, TC1624081, TC1611797, TC1598158, TC1573005, TC1591349
DoTS DT.101200697, DT.110542880, DT.110542869, DT.101737492, DT.492212, DT.99849773, DT.97343317, DT.91592836, DT.91386244, DT.94230716, DT.94230691
NIA Mouse Gene Index U013050
EC 3.6.5.-
Consensus CDS Project CCDS25130.1, CCDS48861.1, CCDS48862.1
International Mouse Phenotyping Consortium Status Rhot1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000219 VEGA Gene Model | MGI Sequence Detail 58468 C57BL/6J ±  kb
transcript OTTMUST00000000643 VEGA | MGI Sequence Detail 3297 Not Applicable 
polypeptide OTTMUSP00000000282 VEGA | MGI Sequence Detail 704 Not Applicable 

For the selected sequences
All sequences(103) RefSeq(13) UniProt(3)
Polymorphisms
SNPs within 2kb(176 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR013566 EF hand associated, type-1
InterPro IPR013567 EF hand associated, type-2
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR020860 MIRO
InterPro IPR013684 Mitochondrial Rho-like
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR021181 Small GTPase superfamily, mitochondrial rho type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013985 mitochondrial Rho GTPase 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:216408 Nguyen TT, et al., Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3631-40
All references(46)
Other
accession IDs
MGI:1891738, MGI:1924850, MGI:2144011, MGI:2144268

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory