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Gmip Gene Detail
Summary
  • Symbol
    Gmip
  • Name
    Gem-interacting protein
  • Synonyms
    5031419I10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926066
    NCBI Gene: 78816
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70261329-70274520 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 33.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    93 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926066
protein coding gene Chr8:70260912-70274520 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033677
protein coding gene Chr8:70021866-70035005 (+)
A/J MGP_AJ_G0033660
protein coding gene Chr8:67185529-67199886 (+)
AKR/J MGP_AKRJ_G0033585
protein coding gene Chr8:69088431-69101553 (+)
BALB/cJ MGP_BALBcJ_G0033656
protein coding gene Chr8:67408502-67421662 (+)
C3H/HeJ MGP_C3HHeJ_G0033366
protein coding gene Chr8:69744314-69759167 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034173
protein coding gene Chr8:72683317-72698424 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031117
protein coding gene Chr8:62012186-62026270 (+)
CAST/EiJ MGP_CASTEiJ_G0032691
protein coding gene Chr8:69211202-69227035 (+)
CBA/J MGP_CBAJ_G0033344
protein coding gene Chr8:75340114-75353254 (+)
DBA/2J MGP_DBA2J_G0033498
protein coding gene Chr8:66911822-66925641 (+)
FVB/NJ MGP_FVBNJ_G0033439
protein coding gene Chr8:66004937-66018200 (+)
LP/J MGP_LPJ_G0033585
protein coding gene Chr8:70084302-70097503 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033483
protein coding gene Chr8:77997156-78010241 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034191
protein coding gene Chr8:69270547-69284732 (+)
PWK/PhJ MGP_PWKPhJ_G0032399
protein coding gene Chr8:66194466-66209448 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032235
protein coding gene Chr8:68251985-68265680 (+)
WSB/EiJ MGP_WSBEiJ_G0032806
protein coding gene Chr8:69637866-69652953 (+)



Homology
more
  • Human Ortholog
    GMIP, GEM interacting protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GMIP, GEM interacting protein
  • Synonyms
    ARHGAP46
  • Links
    NCBI Gene ID: 51291
    neXtProt AC: NX_Q9P107
    UniProt: Q9P107

  • Chr Location
    19p13.11; chr19:19629476-19643657 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036246 Ensembl Gene Model | MGI Sequence Detail 13192 C57BL/6J ±  kb
    transcript ENSMUST00000036074 Ensembl | MGI Sequence Detail 3933 Not Applicable  
    polypeptide ENSMUSP00000045676 Ensembl | MGI Sequence Detail 971 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 49
      cDNA 48
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:307297 Ota H, et al., Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA. Nat Commun. 2014 Jul 30;5:4532

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory