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Usp54 Gene Detail
Summary
  • Symbol
    Usp54
  • Name
    ubiquitin specific peptidase 54
  • Synonyms
    4930429G18Rik, C030002J06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926037
    NCBI Gene: 78787
Location & Maps
more
  • Sequence Map
    Chr14:20548912-20618354 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      69443 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 11.53 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    USP54, ubiquitin specific peptidase 54
  • Vertebrate Orthologs
    11
  • Human Ortholog
    USP54, ubiquitin specific peptidase 54
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA137L10.3, bA137L10.4, C10orf29
  • Links
    NCBI Gene ID: 159195
    neXtProt AC: NX_Q70EL1

  • Chr Location
    10q22.2; chr10:73497538-73591342 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 90902
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: USP54
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025216 VEGA Gene Model | MGI Sequence Detail 69443 C57BL/6J ±  kb
transcript OTTMUST00000062067 VEGA | MGI Sequence Detail 5756 Not Applicable  
polypeptide OTTMUSP00000030552 VEGA | MGI Sequence Detail 1588 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    188 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017193 inactive ubiquitin carboxyl-terminal hydrolase 54
  • InterPro Domains
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR028889 Ubiquitin specific protease domain
Molecular
Reagents
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  • All nucleic 71
    cDNA 71

    Microarray probesets 4
Other
Accession IDs
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MGI:2145598, MGI:2442602
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory