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Cpxm2 Gene Detail
Summary
  • Symbol
    Cpxm2
  • Name
    carboxypeptidase X 2 (M14 family)
  • Synonyms
    4632435C11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926006
    NCBI Gene: 55987
Location & Maps
more
  • Sequence Map
    Chr7:132032687-132154739 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      122053 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    CPXM2, carboxypeptidase X (M14 family), member 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CPXM2, carboxypeptidase X (M14 family), member 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CPX2, UNQ676
  • Links
    NCBI Gene ID: 119587
    neXtProt AC: NX_Q8N436

  • Chr Location
    10q26.13; chr10:123722291-123891984 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 69259
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: CPXM2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025187 VEGA Gene Model | MGI Sequence Detail 122053 C57BL/6J ±  kb
transcript OTTMUST00000062013 VEGA | MGI Sequence Detail 3498 Not Applicable  
polypeptide OTTMUSP00000030523 VEGA | MGI Sequence Detail 764 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    644 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR008969 Carboxypeptidase-like, regulatory domain
    IPR014766 Carboxypeptidase, regulatory domain
    IPR000421 Coagulation factor 5/8 C-terminal domain
    IPR008979 Galactose-binding domain-like
    IPR000834 Peptidase M14, carboxypeptidase A
Molecular
Reagents
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  • All nucleic 18
    cDNA 18

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:50715 Xin X, et al., Identification of mouse CPX-2, a novel member of the metallocarboxypeptidase gene family: cDNA cloning, mRNA distribution, and protein expression and characterization. DNA Cell Biol. 1998 Oct;17(10):897-909
  • Latest
    J:197180 Buniello A, et al., Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory