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March2 Gene Detail
Summary
  • Symbol
    March2
  • Name
    membrane-associated ring finger (C3HC4) 2
  • Synonyms
    9530046H09Rik, MGC:7259
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925915
    NCBI Gene: 224703
  • Gene Overview
    MyGene.info: MARCH2
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:33685692-33718670 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925915
protein coding gene Chr17:33685692-33718677 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023534
protein coding gene Chr17:33603191-33648859 (-)
A/J MGP_AJ_G0023493
protein coding gene Chr17:32448264-32493179 (-)
AKR/J MGP_AKRJ_G0023459
protein coding gene Chr17:32832331-32867626 (-)
BALB/cJ MGP_BALBcJ_G0023497
protein coding gene Chr17:32600894-32633934 (-)
C3H/HeJ MGP_C3HHeJ_G0023260
protein coding gene Chr17:33177139-33210094 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023941
protein coding gene Chr17:34843637-34881726 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021414
protein coding gene Chr17:29976994-30006378 (-)
CAST/EiJ MGP_CASTEiJ_G0022762
protein coding gene Chr17:33289526-33331422 (-)
CBA/J MGP_CBAJ_G0023236
protein coding gene Chr17:36247462-36285854 (-)
DBA/2J MGP_DBA2J_G0023365
protein coding gene Chr17:31841235-31874460 (-)
FVB/NJ MGP_FVBNJ_G0023334
protein coding gene Chr17:31694093-31730423 (-)
LP/J MGP_LPJ_G0023443
protein coding gene Chr17:33890152-33924411 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023354
protein coding gene Chr17:35304910-35343340 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023981
protein coding gene Chr17:33154412-33189886 (-)
PWK/PhJ MGP_PWKPhJ_G0022510
protein coding gene Chr17:30733301-30767115 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022326
protein coding gene Chr17:31136451-31169307 (-)
WSB/EiJ MGP_WSBEiJ_G0022821
protein coding gene Chr17:33200021-33236581 (-)



Homology
more
  • Human Ortholog
    MARCH2, membrane associated ring-CH-type finger 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MARCH2, membrane associated ring-CH-type finger 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC240, MARCH-II, RNF172
  • Links
    NCBI Gene ID: 51257
    neXtProt AC: NX_Q9P0N8
    UniProt: Q9P0N8

  • Chr Location
    19p13.2; chr19:8413272-8439021 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079557 Ensembl Gene Model | MGI Sequence Detail 32979 C57BL/6J ±  kb
transcript ENSMUST00000186022 Ensembl | MGI Sequence Detail 2470 Not Applicable  
polypeptide ENSMUSP00000139724 Ensembl | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:195247 Han SO, et al., MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound beta(2)-adrenergic receptors. J Cell Biol. 2012 Nov 26;199(5):817-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory