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Brd8
Gene Detail
Symbol

Name
ID
Brd8
bromodomain containing 8
MGI:1925906
Synonyms
2610007E11Rik, 4432404P07Rik, p120, SMAP
Feature Type
protein coding gene
Genetic Map
Chromosome 18
18.69 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:34598615-34624601 bp, - strand
From VEGA annotation of GRCm38

  25987 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41790  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Brd8

Human
homologs
Human Homolog BRD8, bromodomain containing 8
NCBI Gene ID 10902
neXtProt AC  NX_Q9H0E9
Human Synonyms  p120, SMAP, SMAP2
Human Chr (Location)  5q31; chr5:138139766-138178669 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(33) : Gene trapped(31) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Brd8 interacts with 259 markers (Mir1b, Mir10a, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process chromatin modification, histone H2A acetylation, ...
Component mitochondrion, NuA4 histone acetyltransferase complex, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (61)    Tissues (29)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 50
RT-PCR 11
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(20) Primer pair(2)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000017276 (Evidence)
Ensembl Gene ModelENSMUSG00000003778 (Evidence)
Entrez Gene78656 (Evidence)
DFCITC1624956, TC1584278, TC1574267, TC1635320, TC1723666, TC1714867, TC1645411, TC1655412
NIA Mouse Gene IndexU038309
Consensus CDS ProjectCCDS50248.1, CCDS70879.1, CCDS70880.1
International Mouse Knockout Project StatusBrd8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017276 VEGA Gene Model | MGI Sequence Detail 25987 C57BL/6J ±  kb
transcript OTTMUST00000041869 VEGA | MGI Sequence Detail 3869 Not Applicable 
polypeptide OTTMUSP00000018830 VEGA | MGI Sequence Detail 954 Not Applicable 

For the selected sequences
All sequences(83) RefSeq(19) UniProt(7)
Polymorphisms
SNPs within 2kb(188 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
Protein Ontology PR:000004809 bromodomain-containing protein 8
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)
Other
accession IDs
MGI:1918037

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory