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Brd8
Gene Detail
Symbol

Name
ID
Brd8
bromodomain containing 8
MGI:1925906
Synonyms
2610007E11Rik, 4432404P07Rik, p120, SMAP
Feature Type
protein coding gene
Genetic Map
Chromosome 18
18.69 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:34598615-34624601 bp, - strand
From VEGA annotation of GRCm38

  25987 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41790  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: BRD8
Gene Tree: Brd8

Human
homologs
BRD8, bromodomain containing 8
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10902
neXtProt AC: NX_Q9H0E9

Human Synonyms: p120, SMAP, SMAP2

Human Chr (Location): 5q31; chr5:138139766-138178669 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(31) : Gene trapped(29) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Brd8 interacts with 258 markers (Mir1b, Mir10a, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process chromatin modification, histone H2A acetylation, ...
Component mitochondrion, NuA4 histone acetyltransferase complex, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (61)    Tissues (29)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 50
RT-PCR 11
cDNA source data(17)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase brd8 ; ZFIN brd8    NEW 
Molecular
reagents
All nucleic(22) cDNA(20) Primer pair(2)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000017276 (Evidence)
Ensembl Gene Model ENSMUSG00000003778 (Evidence)
Entrez Gene 78656 (Evidence)
DFCI TC1574267, TC1584278, TC1624956, TC1635320, TC1645411, TC1655412, TC1714867, TC1723666
NIA Mouse Gene Index U038309
Consensus CDS Project CCDS50248.1, CCDS70879.1, CCDS70880.1
International Mouse Phenotyping Consortium Status Brd8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017276 VEGA Gene Model | MGI Sequence Detail 25987 C57BL/6J ±  kb
transcript OTTMUST00000041869 VEGA | MGI Sequence Detail 3869 Not Applicable 
polypeptide OTTMUSP00000018830 VEGA | MGI Sequence Detail 954 Not Applicable 

For the selected sequences
All sequences(87) RefSeq(26) UniProt(4)
Polymorphisms
SNPs within 2kb(188 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
Protein Ontology PR:000004809 bromodomain-containing protein 8
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:1918037

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory