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Brd8 Gene Detail
Summary
  • Symbol
    Brd8
  • Name
    bromodomain containing 8
  • Synonyms
    2610007E11Rik, 4432404P07Rik, p120, SMAP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925906
    NCBI Gene: 78656
  • Gene Overview
    MyGene.info: BRD8
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34598615-34624601 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 18.69 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925906
protein coding gene Chr18:34598615-34624863 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024244
protein coding gene Chr18:32808767-32846813 (-)
A/J MGP_AJ_G0024210
protein coding gene Chr18:31712430-31738991 (-)
AKR/J MGP_AKRJ_G0024179
protein coding gene Chr18:32615720-32642613 (-)
BALB/cJ MGP_BALBcJ_G0024210
protein coding gene Chr18:31769509-31795940 (-)
C3H/HeJ MGP_C3HHeJ_G0023978
protein coding gene Chr18:32631492-32658849 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024652
protein coding gene Chr18:34079742-34107621 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022093
protein coding gene Chr18:31855220-31879627 (-)
CAST/EiJ MGP_CASTEiJ_G0023453
protein coding gene Chr18:32581982-32607134 (-)
CBA/J MGP_CBAJ_G0023946
protein coding gene Chr18:35012632-35043762 (-)
DBA/2J MGP_DBA2J_G0024078
protein coding gene Chr18:31368214-31394025 (-)
FVB/NJ MGP_FVBNJ_G0024044
protein coding gene Chr18:31054034-31079772 (-)
LP/J MGP_LPJ_G0024159
protein coding gene Chr18:32903685-32929576 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024072
protein coding gene Chr18:36282878-36309097 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024700
protein coding gene Chr18:32444326-32469870 (-)
PWK/PhJ MGP_PWKPhJ_G0023196
protein coding gene Chr18:31559287-31585026 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023005
protein coding gene Chr18:32713737-32742048 (-)
WSB/EiJ MGP_WSBEiJ_G0023516
protein coding gene Chr18:32363114-32390206 (-)



Homology
more
  • Human Ortholog
    BRD8, bromodomain containing 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BRD8, bromodomain containing 8
    Orthology source: HomoloGene, HGNC
  • Synonyms
    p120, SMAP, SMAP2
  • Links
    NCBI Gene ID: 10902
    neXtProt AC: NX_Q9H0E9
    UniProt: Q9H0E9

  • Chr Location
    5q31.2; chr5:138139766-138178669 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41790
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BRD8
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003778 Ensembl Gene Model | MGI Sequence Detail 25987 C57BL/6J ±  kb
transcript ENSMUST00000115765 Ensembl | MGI Sequence Detail 3869 Not Applicable  
polypeptide ENSMUSP00000111431 Ensembl | MGI Sequence Detail 954 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 21
    Primer pair 2

    Microarray probesets 9
Other
Accession IDs
less
MGI:1918037
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:243553 Fisher CL, et al., An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Res. 2017 Dec 1;45(21):e174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory