About   Help   FAQ
Bola3 Gene Detail
Summary
  • Symbol
    Bola3
  • Name
    bolA-like 3 (E. coli)
  • Synonyms
    1810056O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925903
    NCBI Gene: 78653
Location & Maps
more
  • Sequence Map
    Chr6:83349147-83360136 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10990 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    BOLA3, bolA family member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BOLA3, bolA family member 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MMDS2
  • Links
    NCBI Gene ID: 388962
    neXtProt AC: NX_Q53S33

  • Chr Location
    2p13.1; chr2:74135401-74147912 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human BOLA3 associations

Human Disease Mouse Models
       Multiple Mitochondrial Dysfunctions Syndrome 2; MMDS2   OMIM: 614299
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    3
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Bola3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027009 VEGA Gene Model | MGI Sequence Detail 10990 C57BL/6J ±  kb
transcript OTTMUST00000066755 VEGA | MGI Sequence Detail 583 Not Applicable  
polypeptide OTTMUSP00000033503 VEGA | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    94 from dbSNP Build 137
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004788 BolA-like protein 3
  • InterPro Domains
    IPR002634 BolA protein
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 5
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory