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Ccdc166 Gene Detail
Summary
  • Symbol
    Ccdc166
  • Name
    coiled-coil domain containing 166
  • Synonyms
    2410075B13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925902
    NCBI Gene: 223648
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75851721-75854134 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 35.18 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    152 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925902
protein coding gene Chr15:75851721-75854304 (-)
129S1/SvImJ ENSMUSG00200052598
protein coding gene Chr15:72969213-72971796 (-)
A/J ENSMUSG00195045708
protein coding gene Chr15:72943632-72946215 (-)
AKR/J ENSMUSG00220046082
protein coding gene Chr15:72954686-72957269 (-)
BALB/cJ ENSMUSG00180046024
protein coding gene Chr15:72770361-72772944 (-)
C3H/HeJ ENSMUSG00175049898
protein coding gene Chr15:73132238-73134821 (-)
C57BL/6NJ ENSMUSG00215049957
protein coding gene Chr15:72860787-72863370 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005045567
protein coding gene Chr15:72477970-72480553 (-)
CBA/J ENSMUSG00210044306
protein coding gene Chr15:72907506-72910089 (-)
DBA/2J ENSMUSG00185047167
protein coding gene Chr15:72886222-72888805 (-)
FVB/NJ ENSMUSG00205048123
protein coding gene Chr15:72636918-72639501 (-)
JF1/MsJ ENSUMUG00000054796
protein coding gene Chr15:72544053-72546635 (-)
LP/J ENSMUSG00230052540
protein coding gene Chr15:76250195-76252778 (-)
NOD/ShiLtJ ENSMUSG00190030137
protein coding gene Chr15:72889874-72892457 (-)
NZO/HlLtJ ENSMUSG00225049850
protein coding gene Chr15:76554712-76557295 (-)
PWK/PhJ ENSLUMG00010040117
protein coding gene Chr15:72824906-72827488 (-)
SPRET/EiJ ENSMSPG00010047928
protein coding gene Chr15:74436854-74439430 (-)
WSB/EiJ ENSIUOG00005037387
protein coding gene Chr15:72946963-72949546 (-)



Homology
more
  • Human Ortholog
    CCDC166, coiled-coil domain containing 166
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC166, coiled-coil domain containing 166
  • Links
    NCBI Gene ID: 100130274
    UniProt: P0CW27

  • Chr Location
    8q24.3; chr8:143706694-143708109 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    3
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Ccdc166
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 223648 NCBI Gene Model | MGI Sequence Detail 2414 C57BL/6J ±  kb
transcript NM_001163518 RefSeq | MGI Sequence Detail 2414 C57BL/6  
polypeptide NP_666171 RefSeq | MGI Sequence Detail 449 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR032777 Domain of unknown function DUF4515
  • GlyGen
    S4R181 1 site
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 5
References
more
  • Summaries
    All 51
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 30
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory