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Lsm6 Gene Detail
Summary
  • Symbol
    Lsm6
  • Name
    LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    1500031N17Rik, 2410088K19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925901
    NCBI Gene: 78651
  • Gene Overview
    MyGene.info: LSM6
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:78804865-78821140 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 37.22 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925901
protein coding gene Chr8:78804865-78821152 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033808
protein coding gene Chr8:79448037-79465900 (-)
A/J MGP_AJ_G0033790
protein coding gene Chr8:76272347-76288703 (-)
AKR/J MGP_AKRJ_G0033717
protein coding gene Chr8:78566025-78582295 (-)
BALB/cJ MGP_BALBcJ_G0033784
protein coding gene Chr8:76381765-76398212 (-)
C3H/HeJ MGP_C3HHeJ_G0033493
protein coding gene Chr8:79186353-79202968 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034304
protein coding gene Chr8:82489138-82513998 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031245
protein coding gene Chr8:70367742-70383936 (-)
CAST/EiJ MGP_CASTEiJ_G0032824
protein coding gene Chr8:78526611-78542857 (-)
CBA/J MGP_CBAJ_G0033472
protein coding gene Chr8:85422083-85438292 (-)
DBA/2J MGP_DBA2J_G0033625
protein coding gene Chr8:75966979-75984813 (-)
FVB/NJ MGP_FVBNJ_G0033570
protein coding gene Chr8:74958285-74975092 (-)
LP/J MGP_LPJ_G0033715
protein coding gene Chr8:79536914-79553187 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033613
protein coding gene Chr8:87993810-88010420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034321
protein coding gene Chr8:78587283-78603699 (-)
PWK/PhJ MGP_PWKPhJ_G0032527
protein coding gene Chr8:75244971-75261361 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032365
protein coding gene Chr8:77397912-77414249 (-)
WSB/EiJ MGP_WSBEiJ_G0032937
protein coding gene Chr8:78913941-78930198 (-)



Homology
more
  • Human Ortholog
    LSM6, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LSM6, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
    Orthology source: HomoloGene, HGNC
  • Synonyms
    YDR378C
  • Links
    NCBI Gene ID: 11157
    neXtProt AC: NX_P62312
    UniProt: P62312

  • Chr Location
    4q31.22; chr4:146175683-146204436 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Genomic Mutations
    1 involving Lsm6
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031683 Ensembl Gene Model | MGI Sequence Detail 16276 C57BL/6J ±  kb
transcript ENSMUST00000051867 Ensembl | MGI Sequence Detail 2107 Not Applicable  
polypeptide ENSMUSP00000049722 Ensembl | MGI Sequence Detail 80 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 51
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1916265, MGI:2142614
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory