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Zfp449 Gene Detail
Summary
  • Symbol
    Zfp449
  • Name
    zinc finger protein 449
  • Synonyms
    9530049C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925869
    NCBI Gene: 78619
Location & Maps
more
  • Sequence Map
    ChrX:56346400-56365674 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19275 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 30.06 cM, cytoband A4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ZNF449, zinc finger protein 449
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZNF449, zinc finger protein 449
    Orthology source: HomoloGene
  • Synonyms
    ZSCAN19
  • Links
    NCBI Gene ID: 203523
    neXtProt AC: NX_Q6P9G9

  • Chr Location
    Xq26.3; chrX:135344757-135363413 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Targeted
    1
Mice homozygous for a knock-out allele exhibit normal skeletal growth and cartilage homeostasis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017518 VEGA Gene Model | MGI Sequence Detail 19275 C57BL/6J ±  kb
transcript OTTMUST00000042564 VEGA | MGI Sequence Detail 3738 Not Applicable  
polypeptide OTTMUSP00000019128 VEGA | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    95 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:225376 Okada K, et al., Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis. PLoS One. 2014;9(12):e115169

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory