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Jade1
Gene Detail
 Symbol
Name
ID
Jade1
jade family PHD finger 1
MGI:1925835
Synonyms D530048A03Rik, mKIAA1807, Phf17
Feature Type protein coding gene
Genetic Map
Chromosome 3
19.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:41555734-41616862 bp, + strand
From Ensembl annotation of GRCm38

  61129 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18162  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Jade1

Human
homologs
Human Homolog JADE1, jade family PHD finger 1
NCBI Gene ID 79960
neXtProt AC  NX_Q6IE81
Human Synonyms  PHF17
Human Chr (Location)  4q26-q27; chr4:128809623-128875224 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(257) : Gene trapped(255) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Though mice homozygous for mutations of this locus show no overt phenotype at birth, fewer survive to weaning than expected by Mendelian ratios.
 
Interactions
Jade1 interacts with 415 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process apoptotic process, histone H3 acetylation, ...
Component cytoplasm, histone acetyltransferase complex, ...
Function metal ion binding, RNA polymerase II transcription coactivator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (97)    Tissues (63)    Images (2)
Theiler Stages: 2, 3, 4, 5, 9, 11, 14, 20, 21, 23, 24, 28
Assay TypeResults
RNA in situ 24
In situ reporter (knock in) 44
Northern blot 10
RT-PCR 19
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(19) Primer pair(4)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000025764 (Evidence)
Entrez Gene269424 (Evidence)
DFCITC1577207, TC1603114, TC1633909, TC1704883
DoTSDT.101388295, DT.101390268, DT.493371, DT.91294185, DT.94129618
NIA Mouse Gene IndexU003202
Consensus CDS ProjectCCDS17331.1
International Mouse Knockout Project StatusJade1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025764 Ensembl Gene Model | MGI Sequence Detail 61129 C57BL/6J ±  kb
transcript ENSMUST00000168086 Ensembl | MGI Sequence Detail 5514 Not Applicable 
polypeptide ENSMUSP00000131441 Ensembl | MGI Sequence Detail 834 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(14) UniProt(2)
Polymorphisms SNPs within 2kb(369 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019542 Enhancer of polycomb-like, N-terminal
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000012644 protein Jade-1
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:191148 Foy RL, et al., Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1. Hum Mol Genet. 2012 Dec 15;21(26):5456-71
All references(44)
Other
accession IDs
MGI:2139907

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory