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Htra3
Gene Detail
Symbol

Name
ID
Htra3
HtrA serine peptidase 3
MGI:1925808
Synonyms
2210021K23Rik, 9530081K03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
18.49 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:35652041-35679782 bp, - strand
From VEGA annotation of GRCm38

  27742 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12697  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: serine protease, HTRA type
Gene Tree: Htra3

Human
homologs
Human Homolog HTRA3, HtrA serine peptidase 3
NCBI Gene ID 94031
neXtProt AC  NX_P83110
Human Synonyms  Prsp, Tasp
Human Chr (Location)  4p16.1; chr4:8269760-8307111 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Chemically induced (ENU)(1) Radiation induced(4) Targeted(3)
Genomic Mutations involving Htra3 (5)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(4)   
Interactions
Htra3 interacts with 162 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(68)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(68) cDNA(68)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000024097 (Evidence)
Ensembl Gene ModelENSMUSG00000029096 (Evidence)
Entrez Gene78558 (Evidence)
UniGene274255
DFCITC1585170, TC1579356, TC1596200
DoTSDT.94242945, DT.91596256, DT.492443, DT.101356522
NIA Mouse Gene IndexU026114
EC3.4.21.-
Consensus CDS ProjectCCDS19233.1, CCDS39071.1
International Mouse Knockout Project StatusHtra3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024097 VEGA Gene Model | MGI Sequence Detail 27742 C57BL/6J ±  kb
transcript OTTMUST00000058943 VEGA | MGI Sequence Detail 2732 Not Applicable 
polypeptide OTTMUSP00000028630 VEGA | MGI Sequence Detail 459 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(287 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000867 Insulin-like growth factor-binding protein, IGFBP
InterPro IPR009030 Insulin-like growth factor binding protein, N-terminal
InterPro IPR002350 Kazal domain
InterPro IPR001478 PDZ domain
InterPro IPR001940 Peptidase S1C
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000031746 serine protease HTRA3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:1921510

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory