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Icam4 Gene Detail
Summary
  • Symbol
    Icam4
  • Name
    intercellular adhesion molecule 4, Landsteiner-Wiener blood group
  • Synonyms
    1810015M19Rik, Cd242
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925619
    NCBI Gene: 78369
Location & Maps
more
  • Sequence Map
    Chr9:21029373-21030531 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1159 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.69 cM, cytoband A3
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ICAM4, intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ICAM4, intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CD242, LW
  • Links
    NCBI Gene ID: 3386
    neXtProt AC: NX_Q14773

  • Chr Location
    19p13.2; chr19:10286967-10288584 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Gene trapped
    1
  • Targeted
    1
  • Incidental Mutations
Mice homozygous for a null allele exhibit decreased erythroblastic island formation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78369 NCBI Gene Model | MGI Sequence Detail 1159 C57BL/6J ±  kb
transcript NM_023892 RefSeq | MGI Sequence Detail 907 Not Specified  
polypeptide Q9ERM2 UniProt | EBI | MGI Sequence Detail 262 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    12 from dbSNP Build 142
  • PCR
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001359 intercellular adhesion molecule 4
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR013768 Intercellular adhesion molecule, N-terminal
    IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
Molecular
Reagents
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  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory