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Ankrd23 Gene Detail
Summary
  • Symbol
    Ankrd23
  • Name
    ankyrin repeat domain 23
  • Synonyms
    1110058D09Rik, 2310041C05Rik, Darp, MARP3, MARP3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925571
    NCBI Gene: 78321
  • Gene Overview
    MyGene.info: ANKRD23
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36530193-36536556 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 15.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925571
protein coding gene Chr1:36530188-36536883 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014039
protein coding gene Chr1:31181593-31198389 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0015061
protein coding gene Chr1:33215374-33233757 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014843
protein coding gene Chr1:34593379-34612033 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ANKRD23, ankyrin repeat domain 23
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ANKRD23, ankyrin repeat domain 23
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DARP, MARP3
  • Links
    NCBI Gene ID: 200539
    neXtProt AC: NX_Q86SG2
    UniProt: Q86SG2

  • Chr Location
    2q11.2; chr2:96837914-96844021 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    6 phenotype references
Mice homozygous for a knock-out allele are viable, fertile, and exhibit no apparent cardiac phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 78321 NCBI Gene Model | MGI Sequence Detail 6364 C57BL/6J ±  kb
transcript NM_001310521 RefSeq | MGI Sequence Detail 2321 C57BL/6  
polypeptide NP_705722 RefSeq | MGI Sequence Detail 306 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 2
Other
Accession IDs
less
MGI:1916019, MGI:2138368
References
more
  • Summaries
    All 28
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:240063 Lange S, et al., MLP and CARP are linked to chronic PKCalpha signalling in dilated cardiomyopathy. Nat Commun. 2016 Jun 29;7:12120

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory