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Tbcel Gene Detail
Summary
  • Symbol
    Tbcel
  • Name
    tubulin folding cofactor E-like
  • Synonyms
    E130107N23Rik, Lrrc35
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925543
    NCBI Gene: 272589
Location & Maps
more
  • Sequence Map
    Chr9:42412316-42507809 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      95494 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 23.71 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TBCEL, tubulin folding cofactor E-like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TBCEL, tubulin folding cofactor E-like
    Orthology source: HomoloGene
  • Synonyms
    El, LRRC35
  • Links
    NCBI Gene ID: 219899
    neXtProt AC: NX_Q5QJ74

  • Chr Location
    11q23.3; chr11:121024094-121089647 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 16120
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TBCEL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033562 VEGA Gene Model | MGI Sequence Detail 95494 C57BL/6J ±  kb
transcript OTTMUST00000084519 VEGA | MGI Sequence Detail 3893 Not Applicable  
polypeptide OTTMUSP00000045553 VEGA | MGI Sequence Detail 442 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    743 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016130 tubulin-specific chaperone cofactor E-like protein
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain, L domain-like
    IPR000626 Ubiquitin domain
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
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  • All nucleic 65
    cDNA 65

    Microarray probesets 6
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory