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Klhdc8b
Gene Detail
Symbol

Name
ID
Klhdc8b
kelch domain containing 8B
MGI:1925517
Synonyms
4931406O17Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.37 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:108447636-108461581 bp, - strand
From VEGA annotation of GRCm38

  13946 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45463  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KLHDC8B
Gene Tree: Klhdc8b

Human
homologs
KLHDC8B, kelch domain containing 8B
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 200942
neXtProt AC: NX_Q8IXV7

Human Synonyms: CHL

Human Chr (Location): 3p21.31; chr3:49171120-49176486 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human KLHDC8B

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(11) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klhdc8b interacts with 102 markers (Mir15a, Mir22, Mir28b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cytoplasm
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (2)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 1
cDNA source data(41)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(43) cDNA(42) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000050757 (Evidence)
Ensembl Gene Model ENSMUSG00000032609 (Evidence)
Entrez Gene 78267 (Evidence)
UniGene 283194
DFCI TC1616803, TC1616766, TC1577280, TC1614809
DoTS DT.101295906, DT.101281472, DT.91597432, DT.94178434, DT.110570843, DT.91587724, DT.97352497
NIA Mouse Gene Index U031336
Consensus CDS Project CCDS23526.1
International Mouse Phenotyping Consortium Status Klhdc8b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050757 VEGA Gene Model | MGI Sequence Detail 13946 C57BL/6J ±  kb
transcript OTTMUST00000128637 VEGA | MGI Sequence Detail 2956 Not Applicable 
polypeptide OTTMUSP00000069176 VEGA | MGI Sequence Detail 354 Not Applicable 

For the selected sequences
All sequences(83) RefSeq(16) UniProt(2)
Polymorphisms
SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011043 Galactose oxidase/kelch, beta-propeller
InterPro IPR006652 Kelch repeat type 1
InterPro IPR015915 Kelch-type beta propeller
Protein Ontology PR:000030952 kelch domain-containing protein 8B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory