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Ralgps2
Gene Detail
Symbol

Name
ID
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
MGI:1925505
Synonyms
1810020P17Rik, 2210408F11Rik, 4921528G01Rik, 9130014M22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
67.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:156804166-156939626 bp, - strand
From VEGA annotation of GRCm38

  135461 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23421  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ralgps2

Human
homologs
Human Homolog RALGPS2, Ral GEF with PH domain and SH3 binding motif 2
NCBI Gene ID 55103
neXtProt AC  NX_Q86X27
Human Synonyms  dJ595C2.1
Human Chr (Location)  1q25.2; chr1:178725147-178921842 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(25) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ralgps2 interacts with 442 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process small GTPase mediated signal transduction
Component cytoplasm, membrane, ...
Function guanyl-nucleotide exchange factor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (185)    Tissues (29)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 185
cDNA source data(190)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(192) cDNA(192)
Microarray probesets(7)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049722 VEGA Gene Model | MGI Sequence Detail 135461 C57BL/6J ±  kb
transcript OTTMUST00000126738 VEGA | MGI Sequence Detail 3346 Not Applicable 
polypeptide OTTMUSP00000068511 VEGA | MGI Sequence Detail 590 Not Applicable 

For the selected sequences
All sequences(116) RefSeq(26) UniProt(7)
Polymorphisms
SNPs within 2kb(1456 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1464)
Protein-related
information
ResourceIDDescription
InterPro IPR001895 Guanine-nucleotide dissociation stimulator CDC25
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR023578 Ras guanine nucleotide exchange factor, domain
Protein Ontology PR:000013700 ras-specific guanine nucleotide-releasing factor RalGPS2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(38)
Other
accession IDs
MGI:1916362, MGI:1917389, MGI:1921815, MGI:2138499, MGI:2138540

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory