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Ralgps2
Gene Detail
 Symbol
Name
ID
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
MGI:1925505
Synonyms 1810020P17Rik, 2210408F11Rik, 4921528G01Rik, 9130014M22Rik
Feature Type protein coding gene
Genetic Map
Chromosome 1
67.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:156804166-156939626 bp, - strand
From VEGA annotation of GRCm38

  135461 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23421  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ralgps2

Human
homologs
Human Homolog RALGPS2, Ral GEF with PH domain and SH3 binding motif 2
NCBI Gene ID 55103
neXtProt AC  NX_Q86X27
Human Synonyms  dJ595C2.1
Human Chr (Location)  1q25.2; chr1:178725147-178921842 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(25) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ralgps2 interacts with 442 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process small GTPase mediated signal transduction
Component cytoplasm, membrane, ...
Function guanyl-nucleotide exchange factor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (185)    Tissues (29)    Images (20)
Theiler Stages: 23
Assay TypeResults
RNA in situ 185
cDNA source data(190)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(192) cDNA(192)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000049722 (Evidence)
Ensembl Gene ModelENSMUSG00000026594 (Evidence)
Entrez Gene78255 (Evidence)
UniGene28376
DFCITC1575722, TC1590020, TC1592643, TC1602323, TC1604527, TC1676598
DoTSDT.101402442, DT.101402444, DT.101402446, DT.110922748, DT.489736, DT.490592, DT.55138122, DT.55170784, DT.87056706, DT.91564422, DT.97404169
NIA Mouse Gene IndexU021932, U196079
Consensus CDS ProjectCCDS15396.1, CCDS48405.1, CCDS48406.1
International Mouse Knockout Project StatusRalgps2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049722 VEGA Gene Model | MGI Sequence Detail 135461 C57BL/6J ±  kb
transcript OTTMUST00000126738 VEGA | MGI Sequence Detail 3346 Not Applicable 
polypeptide OTTMUSP00000068511 VEGA | MGI Sequence Detail 590 Not Applicable 

For the selected sequences
All sequences(111) RefSeq(26) UniProt(2)
Polymorphisms SNPs within 2kb(1456 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1464)
Protein-related
information
ResourceIDDescription
InterPro IPR001895 Guanine-nucleotide dissociation stimulator CDC25
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR023578 Ras guanine nucleotide exchange factor, domain
Protein Ontology PR:000013700 ras-specific guanine nucleotide-releasing factor RalGPS2
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(38)
Other
accession IDs
MGI:1916362, MGI:1917389, MGI:1921815, MGI:2138499, MGI:2138540

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory