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Tmem190 Gene Detail
Summary
  • Symbol
    Tmem190
  • Name
    transmembrane protein 190
  • Synonyms
    4930572D21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925302
    NCBI Gene: 78052
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4785936-4787340 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.77 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925302
 protein coding gene Chr7:4784788-4787340 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031561
 protein coding gene Chr7:1722204-1723607 (+)
A/J MGP_AJ_G0031535
 protein coding gene Chr7:1723582-1724986 (+)
AKR/J MGP_AKRJ_G0031464
 protein coding gene Chr7:1787198-1788602 (+)
BALB/cJ MGP_BALBcJ_G0031543
 protein coding gene Chr7:1763539-1764942 (+)
C3H/HeJ MGP_C3HHeJ_G0031264
 protein coding gene Chr7:1765322-1766726 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032004
 protein coding gene Chr7:1786744-1788148 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029128
 protein coding gene Chr7:1463994-1465396 (+)
CAST/EiJ MGP_CASTEiJ_G0030628
 protein coding gene Chr7:1708207-1709611 (+)
CBA/J MGP_CBAJ_G0031222
 protein coding gene Chr7:1979335-1980739 (+)
DBA/2J MGP_DBA2J_G0031381
 protein coding gene Chr7:1697700-1699104 (+)
FVB/NJ MGP_FVBNJ_G0031333
 protein coding gene Chr7:1665045-1666449 (+)
LP/J MGP_LPJ_G0031466
 protein coding gene Chr7:1824597-1826000 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031372
 protein coding gene Chr7:1918826-1920230 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032034
 protein coding gene Chr7:1706711-1708114 (+)
PWK/PhJ MGP_PWKPhJ_G0030356
 protein coding gene Chr7:1871151-1872555 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030181
 protein coding gene Chr7:1749630-1751038 (+)
WSB/EiJ MGP_WSBEiJ_G0030723
 protein coding gene Chr7:1718029-1719432 (+)



Homology
more
  • Human Ortholog
    TMEM190, transmembrane protein 190
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM190, transmembrane protein 190
  • Synonyms
    MDAC1
  • Links
    NCBI Gene ID: 147744
    neXtProt AC: NX_Q8WZ59
    UniProt: Q8WZ59

  • Chr Location
    19q13.42; chr19:55376826-55378246 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a null allele are viable and fertile with no gross abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000013091 Ensembl Gene Model | MGI Sequence Detail 1405 C57BL/6J ±  kb
transcript ENSMUST00000013235 Ensembl | MGI Sequence Detail 589 Not Applicable  
polypeptide ENSMUSP00000013235 Ensembl | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory