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Tmem190 Gene Detail
Summary
  • Symbol
    Tmem190
  • Name
    transmembrane protein 190
  • Synonyms
    4930572D21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925302
    NCBI Gene: 78052
Location & Maps
more
  • Genetic Map
    Chromosome 7, 2.77 cM, cytoband A1
  • Mapping Data
    2 experiments
Homology
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  • Human Ortholog
    TMEM190, transmembrane protein 190
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TMEM190, transmembrane protein 190
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MDAC1
  • Links
    NCBI Gene ID: 147744
    neXtProt AC: NX_Q8WZ59

  • Chr Location
    19q13.42; chr19:55376836-55378244 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    2
  • Targeted
    2
  • Incidental Mutations
    APF
Mice homozygous for a null allele are viable and fertile with no gross abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058304 VEGA Gene Model | MGI Sequence Detail 1405 C57BL/6J ±  kb
transcript OTTMUST00000143179 VEGA | MGI Sequence Detail 589 Not Applicable  
polypeptide OTTMUSP00000074650 VEGA | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    39 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030489 transmembrane protein 190
  • InterPro Domains
    IPR000519 P-type trefoil domain
    IPR028248 Transmembrane protein 190
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
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  • Summaries
    All 22
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory