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Them6 Gene Detail
Summary
  • Symbol
    Them6
  • Name
    thioesterase superfamily member 6
  • Synonyms
    4930572J05Rik, MGC:54796
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925301
    NCBI Gene: 223626
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:74593083-74596222 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.26 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    162 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925301
 protein coding gene Chr15:74593053-74596488 (+)
129S1/SvImJ ENSMUSG00200053035
 protein coding gene Chr15:71696852-71700284 (+)
A/J ENSMUSG00195044159
 protein coding gene Chr15:71766073-71769509 (+)
AKR/J ENSMUSG00220046090
 protein coding gene Chr15:71686622-71690058 (+)
BALB/cJ ENSMUSG00180044191
 protein coding gene Chr15:71538538-71541974 (+)
C3H/HeJ ENSMUSG00175051889
 protein coding gene Chr15:71900475-71903909 (+)
C57BL/6NJ ENSMUSG00215047866
 protein coding gene Chr15:71595701-71599137 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019874
 protein coding gene Chr15:68257186-68260654 (+)
CAST/EiJ ENSTCUG00005042415
 protein coding gene Chr15:71197735-71201170 (+)
CBA/J ENSMUSG00210044068
 protein coding gene Chr15:71675830-71679266 (+)
DBA/2J ENSMUSG00185042448
 protein coding gene Chr15:71621213-71624650 (+)
FVB/NJ ENSMUSG00205043829
 protein coding gene Chr15:71367078-71370515 (+)
JF1/MsJ ENSUMUG00000025763
 protein coding gene Chr15:71260131-71263563 (+)
LP/J ENSMUSG00230051479
 protein coding gene Chr15:74985286-74988723 (+)
NOD/ShiLtJ ENSMUSG00190050286
 protein coding gene Chr15:71732031-71735469 (+)
NZO/HlLtJ ENSMUSG00225051944
 protein coding gene Chr15:75258777-75262214 (+)
PWK/PhJ ENSLUMG00010038665
 protein coding gene Chr15:71537662-71541097 (+)
SPRET/EiJ ENSMSPG00010042600
 protein coding gene Chr15:73221919-73225350 (+)
WSB/EiJ ENSIUOG00005045477
 protein coding gene Chr15:71717837-71721273 (+)



Homology
more
  • Human Ortholog
    THEM6, thioesterase superfamily member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THEM6, thioesterase superfamily member 6
  • Synonyms
    C8orf55, DSCD75
  • Links
    NCBI Gene ID: 51337
    UniProt: Q8WUY1

  • Chr Location
    8q24.3; chr8:142727191-142736938 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Them6
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223626 NCBI Gene Model | MGI Sequence Detail 3140 C57BL/6J ±  kb
transcript NM_198607 RefSeq | MGI Sequence Detail 1600 Not Specified  
polypeptide Q80ZW2 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 48
    Diseases 1
    Gene Ontology 1
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory