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Yipf6 Gene Detail
Summary
  • Symbol
    Yipf6
  • Name
    Yip1 domain family, member 6
  • Synonyms
    A430107J06Rik, MGC:59484
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925179
    NCBI Gene: 77929
  • Gene Overview
    MyGene.info: YIPF6
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:98936321-98949021 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 43.19 cM, cytoband C2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925179
protein coding gene ChrX:98936316-98949021 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035933
protein coding gene ChrX:95342735-95356369 (+)
A/J MGP_AJ_G0035918
protein coding gene ChrX:95400422-95413146 (+)
AKR/J MGP_AKRJ_G0035834
protein coding gene ChrX:98132218-98146421 (+)
BALB/cJ MGP_BALBcJ_G0035901
protein coding gene ChrX:94184788-94197716 (+)
C3H/HeJ MGP_C3HHeJ_G0035610
protein coding gene ChrX:95785153-95797896 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036430
protein coding gene ChrX:98267895-98280567 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033260
protein coding gene ChrX:93247061-93260034 (+)
CAST/EiJ MGP_CASTEiJ_G0034897
protein coding gene ChrX:80114728-80127658 (+)
CBA/J MGP_CBAJ_G0035585
protein coding gene ChrX:101287886-101301291 (+)
DBA/2J MGP_DBA2J_G0035739
protein coding gene ChrX:94657882-94670612 (+)
FVB/NJ MGP_FVBNJ_G0035677
protein coding gene ChrX:94053269-94066080 (+)
LP/J MGP_LPJ_G0035829
protein coding gene ChrX:96336515-96350397 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035712
protein coding gene ChrX:105771855-105786166 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036457
protein coding gene ChrX:95083460-95096814 (+)
PWK/PhJ MGP_PWKPhJ_G0034596
protein coding gene ChrX:77762844-77775838 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034424
protein coding gene ChrX:80960971-80974509 (+)
WSB/EiJ MGP_WSBEiJ_G0035036
protein coding gene ChrX:93803111-93816808 (+)



Homology
more
  • Human Ortholog
    YIPF6, Yip1 domain family member 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    YIPF6, Yip1 domain family member 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FinGER6
  • Links
    NCBI Gene ID: 286451
    neXtProt AC: NX_Q96EC8
    UniProt: Q96EC8

  • Chr Location
    Xq12-q13.1; chrX:68498374-68572413 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    5 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous or hemizygous for an ENU-induced allele exhibit colitis and increased susceptibility to induced colitis with decreased Paneth and goblet cells.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 77929 NCBI Gene Model | MGI Sequence Detail 12701 C57BL/6J ±  kb
transcript NM_207633 RefSeq | MGI Sequence Detail 5195 C57BL/6  
polypeptide Q8BR70 UniProt | EBI | MGI Sequence Detail 236 Not Applicable  
For the selected sequence
Protein
Information
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Molecular
Reagents
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  • All nucleic 68
    cDNA 68

    Microarray probesets 6
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187584 Brandl K, et al., Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12650-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory