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Ube2s Gene Detail
Summary
  • Symbol
    Ube2s
  • Name
    ubiquitin-conjugating enzyme E2S
  • Synonyms
    0910001J09Rik, 6720465F12Rik, E2-EPF
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925141
    NCBI Gene: 77891
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4808014-4812340 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 2.78 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925141
protein coding gene Chr7:4794546-4812590 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031564
protein coding gene Chr7:1734364-1760465 (-)
A/J MGP_AJ_G0031538
protein coding gene Chr7:1748066-1754458 (-)
AKR/J MGP_AKRJ_G0031467
protein coding gene Chr7:1808883-1826776 (-)
BALB/cJ MGP_BALBcJ_G0031546
protein coding gene Chr7:1778352-1796274 (-)
C3H/HeJ MGP_C3HHeJ_G0031267
protein coding gene Chr7:1778291-1797996 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032007
protein coding gene Chr7:1798355-1817350 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029131
protein coding gene Chr7:1475908-1492695 (-)
CAST/EiJ MGP_CASTEiJ_G0030631
protein coding gene Chr7:1719479-1740161 (-)
CBA/J MGP_CBAJ_G0031225
protein coding gene Chr7:1992897-2010368 (-)
DBA/2J MGP_DBA2J_G0031384
protein coding gene Chr7:1709278-1727887 (-)
FVB/NJ MGP_FVBNJ_G0031336
protein coding gene Chr7:1677550-1695004 (-)
LP/J MGP_LPJ_G0031469
protein coding gene Chr7:1837134-1858392 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031375
protein coding gene Chr7:1930225-1949538 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032037
protein coding gene Chr7:1718079-1736065 (-)
PWK/PhJ MGP_PWKPhJ_G0030359
protein coding gene Chr7:1883879-1901495 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030184
protein coding gene Chr7:1761585-1779514 (-)
WSB/EiJ MGP_WSBEiJ_G0030726
protein coding gene Chr7:1731137-1751413 (-)



Homology
more
  • Human Ortholog
    UBE2S, ubiquitin conjugating enzyme E2 S
  • Vertebrate Orthologs
    9
  • Human Ortholog
    UBE2S, ubiquitin conjugating enzyme E2 S
    Orthology source: HomoloGene, HGNC
  • Synonyms
    E2EPF, E2-EPF, EPF5
  • Links
    NCBI Gene ID: 27338
    neXtProt AC: NX_Q16763
    UniProt: Q16763

  • Chr Location
    19q13.42; chr19:55401282-55408146 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 77891 NCBI Gene Model | MGI Sequence Detail 4327 C57BL/6J ±  kb
transcript NM_133777 RefSeq | MGI Sequence Detail 988 C57BL/6  
polypeptide Q921J4 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR023313 Ubiquitin-conjugating enzyme, active site
    IPR000608 Ubiquitin-conjugating enzyme E2
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Molecular
Reagents
less
  • All nucleic 256
    cDNA 256

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913345, MGI:2141820
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory