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Tchp Gene Detail
Summary
  • Symbol
    Tchp
  • Name
    trichoplein, keratin filament binding
  • Synonyms
    A930031F18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925082
    NCBI Gene: 77832
  • Gene Overview
    MyGene.info: TCHP
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:114707760-114722327 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14568 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 55.99 cM, cytoband F
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TCHP, trichoplein keratin filament binding
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TCHP, trichoplein keratin filament binding
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TpMs
  • Links
    NCBI Gene ID: 84260
    neXtProt AC: NX_Q9BT92
    UniProt: Q9BT92

  • Chr Location
    12q24.11; chr12:109880667-109918069 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12686
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TCHP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000014526 VEGA Gene Model | MGI Sequence Detail 14568 C57BL/6J ±  kb
    transcript OTTMUST00000034465 VEGA | MGI Sequence Detail 2882 Not Applicable  
    polypeptide OTTMUSP00000015429 VEGA | MGI Sequence Detail 497 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      70 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000016191 trichoplein keratin filament-binding protein
    • InterPro Domains
      IPR001289 Nuclear transcription factor Y subunit A
      IPR026773 Trichoplein keratin filament-binding protein
    Molecular
    Reagents
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    • All nucleic 32
      cDNA 30
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2141121
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:236569 Inaba H, et al., Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway. J Cell Biol. 2016 Feb 15;212(4):409-23

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory