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Gramd1b Gene Detail
Summary
  • Symbol
    Gramd1b
  • Name
    GRAM domain containing 1B
  • Synonyms
    A930008A22Rik, mKIAA1201
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925037
    NCBI Gene: 235283
  • Alliance
    gene page
  • Transcription Start Sites
    38 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:40293233-40531383 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 21.42 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2580 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925037
 protein coding gene Chr9:40293233-40533614 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034667
 protein coding gene Chr9:38499359-38745118 (-)
A/J MGP_AJ_G0034647
 protein coding gene Chr9:37484262-37734593 (-)
AKR/J MGP_AKRJ_G0034573
 protein coding gene Chr9:38210028-38459489 (-)
BALB/cJ MGP_BALBcJ_G0034638
 protein coding gene Chr9:37260882-37505736 (-)
C3H/HeJ MGP_C3HHeJ_G0034349
 protein coding gene Chr9:38724947-38986586 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035161
 protein coding gene Chr9:39735105-39980322 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032074
 protein coding gene Chr9:37152787-37393294 (-)
CAST/EiJ MGP_CASTEiJ_G0033669
 protein coding gene Chr9:38367061-38703914 (-)
CBA/J MGP_CBAJ_G0034322
 protein coding gene Chr9:41096274-41362843 (-)
DBA/2J MGP_DBA2J_G0034481
 protein coding gene Chr9:37453203-37695020 (-)
FVB/NJ MGP_FVBNJ_G0034421
 protein coding gene Chr9:36678677-36918570 (-)
LP/J MGP_LPJ_G0034562
 protein coding gene Chr9:38777341-39033249 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034465
 protein coding gene Chr9:43148405-43409659 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035180
 protein coding gene Chr9:38140381-38381126 (-)
PWK/PhJ MGP_PWKPhJ_G0033376
 protein coding gene Chr9:37262794-37500864 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033213
 protein coding gene Chr9:38350939-38623928 (-)
WSB/EiJ MGP_WSBEiJ_G0033784
 protein coding gene Chr9:38148076-38400575 (-)



Homology
more
  • Human Ortholog
    GRAMD1B, GRAM domain containing 1B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GRAMD1B, GRAM domain containing 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LINC01059
  • Links
    NCBI Gene ID: 57476
    neXtProt AC: NX_Q3KR37
    UniProt: Q3KR37

  • Chr Location
    11q24.1; chr11:123358299-123627771 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show altered adrenal cholesterol homeostasis due to an inability to transport cholesterol from plasma membrane to the endoplasmic reticulum.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    653
  • Tissues
    8
  • cDNA Data
    88
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040111 Ensembl Gene Model | MGI Sequence Detail 238151 C57BL/6J ±  kb
    transcript ENSMUST00000045682 Ensembl | MGI Sequence Detail 7488 Not Applicable  
    polypeptide ENSMUSP00000048126 Ensembl | MGI Sequence Detail 878 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 91
      Genomic 2
      cDNA 89

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2143098
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:297019 Ferrari A, et al., Aster Proteins Regulate the Accessible Cholesterol Pool in the Plasma Membrane. Mol Cell Biol. 2020 Sep 14;40(19)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    02/16/2021
    MGI 6.16     		The Jackson Laboratory