Gramd1b Gene Detail

Summary

• Symbol
  Gramd1b
• Name
  GRAM domain containing 1B
• Synonyms
  A930008A22Rik, mKIAA1201

• Feature Type
  protein coding gene
• IDs
  MGI:1925037
  NCBI Gene: 235283
• Alliance
  gene page
• Transcription Start Sites
  38 TSS

Location &
Maps

• Sequence Map
  Chr9:40293233-40531383 bp, - strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 21.42 cM, cytoband B
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  2580 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925037	protein coding gene	Chr9:40293233-40531488 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0034667	protein coding gene	Chr9:38499359-38745118 (-)
A/J	MGP_AJ_G0034647	protein coding gene	Chr9:37484262-37734593 (-)
AKR/J	MGP_AKRJ_G0034573	protein coding gene	Chr9:38210028-38459489 (-)
BALB/cJ	MGP_BALBcJ_G0034638	protein coding gene	Chr9:37260882-37505736 (-)
C3H/HeJ	MGP_C3HHeJ_G0034349	protein coding gene	Chr9:38724947-38986586 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0035161	protein coding gene	Chr9:39735105-39980322 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032074	protein coding gene	Chr9:37152787-37393294 (-)
CAST/EiJ	MGP_CASTEiJ_G0033669	protein coding gene	Chr9:38367061-38703914 (-)
CBA/J	MGP_CBAJ_G0034322	protein coding gene	Chr9:41096274-41362843 (-)
DBA/2J	MGP_DBA2J_G0034481	protein coding gene	Chr9:37453203-37695020 (-)
FVB/NJ	MGP_FVBNJ_G0034421	protein coding gene	Chr9:36678677-36918570 (-)
LP/J	MGP_LPJ_G0034562	protein coding gene	Chr9:38777341-39033249 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034465	protein coding gene	Chr9:43148405-43409659 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035180	protein coding gene	Chr9:38140381-38381126 (-)
PWK/PhJ	MGP_PWKPhJ_G0033376	protein coding gene	Chr9:37262794-37500864 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0033213	protein coding gene	Chr9:38350939-38623928 (-)
WSB/EiJ	MGP_WSBEiJ_G0033784	protein coding gene	Chr9:38148076-38400575 (-)

Homology

• Human Ortholog
  GRAMD1B, GRAM domain containing 1B

• Vertebrate Orthologs
  10

• Human Ortholog
  GRAMD1B, GRAM domain containing 1B
  Orthology source: HomoloGene, HGNC
• Synonyms
  LINC01059
• Links
  HGNC:29214

  NCBI Gene ID: 57476

  neXtProt AC: NX_Q3KR37

  UniProt: Q3KR37

  
  
• Chr Location
  11q24.1; chr11:123358299-123627771 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 18223
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: GRAMD1B
• Gene Tree
  Gramd1b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  135
• Endonuclease-mediated
  1
• Gene trapped
  131
• Targeted
  2
• Transposon induced
  1
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  96 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

• External Resources
  FuncBase

Expression

• Assay Results
  22
• Tissues
  8
• cDNA Data
  88
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN gramd1bb

Interactions

• Gramd1b interacts with 441 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

Sequences &
Gene Models

• All Sequences
  113
• RefSeq
  53
• UniProt
  5
• CCDS
  CCDS23081.1
• UniGene
  138434

• Ensembl
  ENSMUSG00000040111 (Evidence)
• NCBI Gene
  235283

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000040111	Ensembl Gene Model | MGI Sequence Detail	238151	C57BL/6J
transcript	ENSMUST00000045682	Ensembl | MGI Sequence Detail	7488	Not Applicable
polypeptide	ENSMUSP00000048126	Ensembl | MGI Sequence Detail	878	Not Applicable

Protein
Information

• UniProt
  5 Sequences
• InterPro Domains
  IPR004182 GRAM domain
  IPR011993 PH-like domain superfamily
  IPR031968 VASt domain

Molecular
Reagents

• All nucleic 91

  Genomic 2

  cDNA 89

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2143098

References

• Summaries
  All 33

  Developmental Gene Expression 3

  Gene Ontology 1

  Phenotypes 8
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Gramd1b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr88966	Chr9:40531461-40531473 (-)	-84 bp
Tssr88965	Chr9:40531362-40531390 (-)	7 bp
Tssr88964	Chr9:40531316-40531334 (-)	58 bp
Tssr88963	Chr9:40531291-40531306 (-)	84 bp
Tssr88962	Chr9:40531103-40531127 (-)	268 bp
Tssr88956	Chr9:40465818-40465825 (-)	65,561 bp
Tssr88955	Chr9:40465802-40465811 (-)	65,576 bp
Tssr88954	Chr9:40465741-40465764 (-)	65,630 bp
Tssr88953	Chr9:40465713-40465734 (-)	65,659 bp
Tssr88952	Chr9:40465683-40465699 (-)	65,692 bp
Tssr88951	Chr9:40465634-40465664 (-)	65,734 bp
Tssr88950	Chr9:40465584-40465595 (-)	65,793 bp
Tssr88945	Chr9:40456230-40456241 (-)	75,147 bp
Tssr88944	Chr9:40456195-40456224 (-)	75,173 bp
Tssr88943	Chr9:40456152-40456176 (-)	75,219 bp
Tssr88942	Chr9:40456137-40456148 (-)	75,240 bp
Tssr88941	Chr9:40456119-40456133 (-)	75,257 bp
Tssr88940	Chr9:40455837-40455844 (-)	75,542 bp
Tssr88939	Chr9:40455781-40455812 (-)	75,586 bp
Tssr88938	Chr9:40455774-40455777 (-)	75,607 bp
Tssr88937	Chr9:40455506-40455520 (-)	75,870 bp
Tssr88936	Chr9:40455443-40455456 (-)	75,933 bp
Tssr88935	Chr9:40455418-40455435 (-)	75,956 bp
Tssr88934	Chr9:40455342-40455384 (-)	76,020 bp
Tssr88912	Chr9:40392435-40392482 (-)	138,924 bp
Tssr88911	Chr9:40392423-40392433 (-)	138,955 bp
Tssr88909	Chr9:40376830-40376847 (-)	154,544 bp
Tssr88908	Chr9:40376426-40376444 (-)	154,948 bp
Tssr88907	Chr9:40376359-40376415 (-)	154,996 bp
Tssr88906	Chr9:40376332-40376358 (-)	155,038 bp
Tssr88905	Chr9:40376213-40376263 (-)	155,145 bp
Tssr88904	Chr9:40376121-40376139 (-)	155,253 bp
Tssr88903	Chr9:40346295-40346337 (-)	185,067 bp
Tssr88902	Chr9:40346205-40346233 (-)	185,164 bp
Tssr88901	Chr9:40346189-40346200 (-)	185,188 bp
Tssr88900	Chr9:40346115-40346131 (-)	185,260 bp
Tssr88895	Chr9:40333260-40333301 (-)	198,102 bp
Tssr88881	Chr9:40306994-40307018 (-)	224,377 bp