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Slf2 Gene Detail
Summary
  • Symbol
    Slf2
  • Name
    SMC5-SMC6 complex localization factor 2
  • Synonyms
    6030443O07Rik, Fam178a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924968
    NCBI Gene: 226151
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:44931119-44983787 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.16 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    331 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924968
protein coding gene Chr19:44918505-44983787 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025177
protein coding gene Chr19:44462475-44517863 (+)
A/J MGP_AJ_G0025154
protein coding gene Chr19:42328265-42381585 (+)
AKR/J MGP_AKRJ_G0025122
protein coding gene Chr19:43683887-43741657 (+)
BALB/cJ MGP_BALBcJ_G0025148
protein coding gene Chr19:42376954-42431665 (+)
C3H/HeJ MGP_C3HHeJ_G0024908
protein coding gene Chr19:43834665-43891247 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025591
protein coding gene Chr19:45551475-45609334 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023005
protein coding gene Chr19:41596570-41648759 (+)
CAST/EiJ MGP_CASTEiJ_G0024373
protein coding gene Chr19:43581884-43641095 (+)
CBA/J MGP_CBAJ_G0024888
protein coding gene Chr19:47864185-47926285 (+)
DBA/2J MGP_DBA2J_G0025020
protein coding gene Chr19:42145712-42198789 (+)
FVB/NJ MGP_FVBNJ_G0024981
protein coding gene Chr19:41912757-41967168 (+)
LP/J MGP_LPJ_G0025106
protein coding gene Chr19:44404265-44460118 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025012
protein coding gene Chr19:47257196-47314943 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025649
protein coding gene Chr19:43763973-43818094 (+)
PWK/PhJ MGP_PWKPhJ_G0024122
protein coding gene Chr19:42052922-42106017 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023926
protein coding gene Chr19:42457790-42514896 (+)
WSB/EiJ MGP_WSBEiJ_G0024443
protein coding gene Chr19:43895687-43959111 (+)



Homology
more
  • Human Ortholog
    SLF2, SMC5-SMC6 complex localization factor 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SLF2, SMC5-SMC6 complex localization factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf6, FAM178A
  • Links
    NCBI Gene ID: 55719
    neXtProt AC: NX_Q8IX21
    UniProt: Q8IX21

  • Chr Location
    10q24.31; chr10:100910230-100965134 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036097 Ensembl Gene Model | MGI Sequence Detail 52669 C57BL/6J ±  kb
transcript ENSMUST00000096053 Ensembl | MGI Sequence Detail 6880 Not Applicable  
polypeptide ENSMUSP00000093758 Ensembl | MGI Sequence Detail 1163 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR026161 FAM178 family
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 8
Other
Accession IDs
less
MGI:2147633
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory