Smim41 MGI Mouse Gene Detail - MGI:1924967 - small integral membrane protein 41

Symbol

Smim41
Name

small integral membrane protein 41
Synonyms

6030408B16Rik

Feature Type

protein coding gene
IDs

MGI:1924967
NCBI Gene: 77717
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr15:101191113-101195307 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 56.68 cM
Mapping Data

2 experiments

SNPs within 2kb

184 from dbSNP Build 142
Strain Annotations

16

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924967	protein coding gene	Chr15:101191040-101195307 (+)
129S1/SvImJ	ENSMUSG00200049077	protein coding gene	Chr15:98405953-98410161 (+)
A/J	ENSMUSG00195045161	protein coding gene	Chr15:98285235-98289423 (+)
AKR/J	ENSMUSG00220047937	protein coding gene	Chr15:98269493-98273713 (+)
BALB/cJ	ENSMUSG00180044876	protein coding gene	Chr15:98175939-98180127 (+)
C3H/HeJ	ENSMUSG00175045461	protein coding gene	Chr15:98465293-98469481 (+)
C57BL/6NJ	ENSMUSG00215050303	protein coding gene	Chr15:98231324-98235544 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0005117	lincRNA gene	Chr15:94992296-94996439 (+)
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210031060	protein coding gene	Chr15:98238478-98242686 (+)
DBA/2J	ENSMUSG00185037418	protein coding gene	Chr15:98275856-98280056 (+)
FVB/NJ	ENSMUSG00205043982	protein coding gene	Chr15:97980314-97984535 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230033121	protein coding gene	Chr15:101629260-101633468 (+)
NOD/ShiLtJ	ENSMUSG00190047945	protein coding gene	Chr15:98215181-98219381 (+)
NZO/HlLtJ	ENSMUSG00225027413	protein coding gene	Chr15:101835825-101840027 (+)
PWK/PhJ	ENSLUMG00010044281	protein coding gene	Chr15:97947189-97951395 (+)
SPRET/EiJ	no annotation
WSB/EiJ	ENSIUOG00005037209	protein coding gene	Chr15:98367925-98372121 (+)

Human Ortholog

SMIM41, small integral membrane protein 41

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SMIM41, small integral membrane protein 41
Links

HGNC:54075

NCBI Gene ID: 113523638
Chr Location

12q13.13; chr12:52079704-52108255 (+) GRCh38

MGI Vertebrate Homology

Smim41 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: SMIM41
Gene Tree

Smim41

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References

1 with disease annotations

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Phenotype Summary

23 phenotype references

All Mutations and Alleles

5
Chemically induced (other)

1
Gene trapped

2
Radiation induced

2
Genomic Mutations

3 involving Smim41
Find Mice (IMSR)

2 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

9

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

36
RefSeq

6
UniProt

3
CCDS

CCDS88850.1

Ensembl

ENSMUSG00000075408 (Evidence)
NCBI Gene

77717

			Length	Strain/Species	Flank
genomic	ENSMUSG00000075408	Ensembl Gene Model \| MGI Sequence Detail	4195	C57BL/6J	± kb
transcript	ENSMUST00000191426	Ensembl \| MGI Sequence Detail	1947	Not Applicable
polypeptide	ENSMUSP00000153762	Ensembl \| MGI Sequence Detail	89	Not Applicable

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UniProt

3 Sequences
InterPro Domains

IPR043383 Reprimo family

IPR060618 Reprimo-like, transmembrane helix domain

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All nucleic 9

cDNA 9

Microarray probesets 2

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MGI:2145959, MGI:6284519

Summaries

All 45

Diseases 1

Gene Ontology 1

Phenotypes 23
Earliest

J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
Latest

J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)

TSS for Smim41:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr133280	Chr15:101191077-101191090 (+)	-29 bp
Tssr133281	Chr15:101191099-101191118 (+)	-4 bp
Tssr133282	Chr15:101191347-101191361 (+)	241 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24