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Defb12 Gene Detail
Summary
  • Symbol
    Defb12
  • Name
    defensin beta 12
  • Synonyms
    9230103N16Rik, mBD-12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924924
    NCBI Gene: 77674
Location & Maps
more
  • Sequence Map
    Chr8:19111931-19114839 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2909 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 10.35 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DEFB105A, defensin beta 105A
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DEFB105A, defensin beta 105A
    Orthology source: HomoloGene
  • Synonyms
    BD-5, DEFB105, DEFB-5
  • Links
    NCBI Gene ID: 245908
    neXtProt AC: NX_Q8NG35

  • Chr Location
    8p23.1; chr8:7820779-7823891 (-)  GRCh38.p2

  • Human Ortholog
    DEFB105B, defensin beta 105B
    Orthology source: HomoloGene
  • Synonyms
    BD-5, DEFB-5
  • Links
    NCBI Gene ID: 504180
    neXtProt AC: NX_Q8NG35

  • Chr Location
    8p23.1; chr8:7487668-7490779 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020595 VEGA Gene Model | MGI Sequence Detail 2909 C57BL/6J ±  kb
transcript OTTMUST00000048799 VEGA | MGI Sequence Detail 1003 Not Applicable  
polypeptide OTTMUSP00000022474 VEGA | MGI Sequence Detail 85 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    13 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 2
    Other 2

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory