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Defb12 Gene Detail
Summary
  • Symbol
    Defb12
  • Name
    defensin beta 12
  • Synonyms
    9230103N16Rik, mBD-12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924924
    NCBI Gene: 77674
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:19111931-19114833 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 10.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924924
protein coding gene Chr8:19111931-19114839 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033411
protein coding gene Chr8:16595261-16596111 (-)
A/J MGP_AJ_G0033392
protein coding gene Chr8:16028055-16030961 (-)
AKR/J MGP_AKRJ_G0033322
protein coding gene Chr8:16511878-16514315 (-)
BALB/cJ MGP_BALBcJ_G0033392
protein coding gene Chr8:16145981-16149414 (-)
C3H/HeJ MGP_C3HHeJ_G0033104
protein coding gene Chr8:16710467-16713372 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033904
protein coding gene Chr8:17133182-17136090 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030870
protein coding gene Chr8:15309154-15312301 (-)
CAST/EiJ MGP_CASTEiJ_G0032427
protein coding gene Chr8:16544193-16547098 (-)
CBA/J MGP_CBAJ_G0033078
protein coding gene Chr8:17899282-17902212 (-)
DBA/2J MGP_DBA2J_G0033232
protein coding gene Chr8:15981752-15984187 (-)
FVB/NJ MGP_FVBNJ_G0033180
protein coding gene Chr8:15984847-15990036 (-)
LP/J MGP_LPJ_G0033325
protein coding gene Chr8:16652334-16653184 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033217
protein coding gene Chr8:18028412-18032099 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033921
protein coding gene Chr8:16516185-16519093 (-)
PWK/PhJ MGP_PWKPhJ_G0032140
protein coding gene Chr8:16000893-16003913 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031981
protein coding gene Chr8:16436966-16440145 (-)
WSB/EiJ MGP_WSBEiJ_G0032543
protein coding gene Chr8:16613457-16614307 (-)



Homology
more
  • Human Ortholog
    DEFB105A, defensin beta 105A
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DEFB105A, defensin beta 105A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BD-5, DEFB105, DEFB-5
  • Links
    NCBI Gene ID: 245908
    neXtProt AC: NX_Q8NG35
    UniProt: Q8NG35

  • Chr Location
    8p23.1; chr8:7821966-7823890 (-)  GRCh38.p7

  • Human Ortholog
    DEFB105B, defensin beta 105B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BD-5, DEFB-5
  • Links
    NCBI Gene ID: 504180
    neXtProt AC: NX_Q8NG35
    UniProt: Q8NG35

  • Chr Location
    8p23.1; chr8:7487669-7489593 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 77674 NCBI Gene Model | MGI Sequence Detail 2903 C57BL/6J ±  kb
transcript NM_152802 RefSeq | MGI Sequence Detail 997 C57BL/6  
polypeptide Q8K4N3 UniProt | EBI | MGI Sequence Detail 78 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory