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Ap5z1
Gene Detail
 Symbol
Name
ID
Ap5z1
adaptor-related protein complex 5, zeta 1 subunit
MGI:1924908
Synonyms C330006K01Rik
Feature Type protein coding gene
Genetic Map
Chromosome 5
81.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:142463931-142478715 bp, + strand
From NCBI annotation of GRCm38

  14785 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18213  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ap5z1

Human
homologs
Human Homolog AP5Z1, adaptor-related protein complex 5, zeta 1 subunit
NCBI Gene ID 9907
neXtProt AC  NX_O43299
Human Synonyms  KIAA0415, SPG48, zeta
Human Chr (Location)  7p22.2; chr7:4775631-4794395 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human AP5Z1
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(9) Targeted(1)
Incidental mutations (data from APF )
Interactions
Ap5z1 interacts with 178 markers (Mir1b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cellular response to DNA damage stimulus, DNA repair, ...
Component AP-5 adaptor complex, cytoplasm, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(66)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(67) cDNA(67)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000039623 (Evidence)
Entrez Gene231855 (Evidence)
UniGene78250
DFCITC1576447, TC1582391, TC1599273, TC1619733, TC1716237, TC1762046
DoTSDT.101128555, DT.101384430, DT.101734633, DT.488734, DT.91332670
NIA Mouse Gene IndexU006391
Consensus CDS ProjectCCDS39361.1
International Mouse Knockout Project StatusAp5z1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 231855 NCBI Gene Model | MGI Sequence Detail 14785 C57BL/6J ±  kb
transcript NM_172725 RefSeq | MGI Sequence Detail 3817 C57BL/6 
polypeptide Q3U829 UniProt | EBI | MGI Sequence Detail 807 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(50 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
Protein Ontology PR:000031470 AP-5 complex subunit zeta-1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory