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Ap5z1
Gene Detail
Symbol

Name
ID
Ap5z1
adaptor-related protein complex 5, zeta 1 subunit
MGI:1924908
Synonyms
C330006K01Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
81.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:142463931-142478715 bp, + strand
From Ensembl annotation of GRCm38

  14785 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18213  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AP5Z1
Gene Tree: Ap5z1

Human
homologs
AP5Z1, adaptor-related protein complex 5, zeta 1 subunit
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9907
neXtProt AC: NX_O43299

Human Synonyms: KIAA0415, SPG48, zeta

Human Chr (Location): 7p22.2; chr7:4775631-4794395 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human AP5Z1

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(9) Targeted(1)
Incidental mutations (data from APF )
Interactions
Ap5z1 interacts with 178 markers (Mir1b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cellular response to DNA damage stimulus, DNA repair, ...
Component AP-5 adaptor complex, cytoplasm, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(66)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100497560    NEW 
Molecular
reagents
All nucleic(67) cDNA(67)
Microarray probesets(7)
Other database
links
Ensembl Gene Model ENSMUSG00000039623 (Evidence)
Entrez Gene 231855 (Evidence)
UniGene 78250
DFCI TC1762046, TC1716237, TC1619733, TC1582391, TC1576447, TC1599273
DoTS DT.101384430, DT.488734, DT.101734633, DT.101128555, DT.91332670
NIA Mouse Gene Index U006391
Consensus CDS Project CCDS39361.1
International Mouse Phenotyping Consortium Status Ap5z1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039623 Ensembl Gene Model | MGI Sequence Detail 14785 C57BL/6J ±  kb
transcript ENSMUST00000038699 Ensembl | MGI Sequence Detail 3817 Not Applicable 
polypeptide ENSMUSP00000041863 Ensembl | MGI Sequence Detail 807 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(50 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
Protein Ontology PR:000031470 AP-5 complex subunit zeta-1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory