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Ap5z1 Gene Detail
Summary
  • Symbol
    Ap5z1
  • Name
    adaptor-related protein complex 5, zeta 1 subunit
  • Synonyms
    C330006K01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924908
    NCBI Gene: 231855
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:142463944-142478710 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 81.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924908
protein coding gene Chr5:142463204-142478716 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030311
protein coding gene Chr5:147693853-147715394 (+)
A/J MGP_AJ_G0030280
protein coding gene Chr5:141378495-141394489 (+)
AKR/J MGP_AKRJ_G0030212
protein coding gene Chr5:145787017-145802081 (+)
BALB/cJ MGP_BALBcJ_G0030297
protein coding gene Chr5:142624602-142639049 (+)
C3H/HeJ MGP_C3HHeJ_G0030008
protein coding gene Chr5:146610443-146626008 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030742
protein coding gene Chr5:153111008-153128480 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027960
protein coding gene Chr5:135194168-135209964 (+)
CAST/EiJ MGP_CASTEiJ_G0029413
protein coding gene Chr5:146060979-146076137 (+)
CBA/J MGP_CBAJ_G0029978
protein coding gene Chr5:159360255-159381701 (+)
DBA/2J MGP_DBA2J_G0030128
protein coding gene Chr5:141154655-141169038 (+)
FVB/NJ MGP_FVBNJ_G0030083
protein coding gene Chr5:140343910-140358591 (+)
LP/J MGP_LPJ_G0030214
protein coding gene Chr5:148316310-148335484 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030114
protein coding gene Chr5:161879566-161894899 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030782
protein coding gene Chr5:145640852-145655366 (+)
PWK/PhJ MGP_PWKPhJ_G0029128
protein coding gene Chr5:140220557-140235595 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028964
protein coding gene Chr5:143377532-143394834 (+)
WSB/EiJ MGP_WSBEiJ_G0029487
protein coding gene Chr5:146434691-146452994 (+)



Homology
more
  • Human Ortholog
    AP5Z1, adaptor related protein complex 5 subunit zeta 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AP5Z1, adaptor related protein complex 5 subunit zeta 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KIAA0415, SPG48, zeta
  • Links
    NCBI Gene ID: 9907
    neXtProt AC: NX_O43299
    UniProt: O43299

  • Chr Location
    7p22.1; chr7:4775617-4794395 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human AP5Z1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039623 Ensembl Gene Model | MGI Sequence Detail 14767 C57BL/6J ±  kb
transcript ENSMUST00000038699 Ensembl | MGI Sequence Detail 3689 Not Applicable  
polypeptide ENSMUSP00000041863 Ensembl | MGI Sequence Detail 807 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 68

    Microarray probesets 7
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory