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Ddx10 Gene Detail
Summary
  • Symbol
    Ddx10
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
  • Synonyms
    4632415A01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924841
    NCBI Gene: 77591
  • Gene Overview
    MyGene.info: DDX10
Location & Maps
more
  • Sequence Map
    Chr9:53098454-53248112 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      149659 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 29.12 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DDX10, DEAD-box helicase 10
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DDX10, DEAD-box helicase 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HRH-J8
  • Links
    NCBI Gene ID: 1662
    neXtProt AC: NX_Q13206

  • Chr Location
    11q22.3; chr11:108665025-108940930 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    19
  • Gene trapped
    18
  • Spontaneous
    1
  • Incidental Mutations
Mice homozygous for a spontaneous allele exhibit craniofacial defects, including decreased cranium length, cleft palate, and short snout, and show reduced body size, body weight, lean body mass, and bone mineral content.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053289 Ensembl Gene Model | MGI Sequence Detail 149659 C57BL/6J ±  kb
transcript ENSMUST00000065630 Ensembl | MGI Sequence Detail 3368 Not Applicable  
polypeptide ENSMUSP00000065198 Ensembl | MGI Sequence Detail 875 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    241 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 64

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143106
References
more
  • Summaries
    All 31
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:223062 Palmer K, et al., Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology. Dev Biol. 2015 Jul 30;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory