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Bcl9 Gene Detail
Summary
  • Symbol
    Bcl9
  • Name
    B cell CLL/lymphoma 9
  • Synonyms
    2610202E01Rik, 8030475K17Rik, A330041G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924828
    NCBI Gene: 77578
  • Gene Overview
    MyGene.info: BCL9
Location & Maps
more
  • Sequence Map
    Chr3:97203662-97297917 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      94256 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    BCL9, B-cell CLL/lymphoma 9
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BCL9, B-cell CLL/lymphoma 9
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LGS
  • Links
    NCBI Gene ID: 607
    neXtProt AC: NX_O00512

  • Chr Location
    1q21; chr1:147541401-147626219 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Bcl9
  • Incidental Mutations
Mice carrying homozygous floxed Bcl9 and Bcl9l alleles, inactivated in muscle cells, exhibit impaired muscle regeneration due to increased apoptosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022435 VEGA Gene Model | MGI Sequence Detail 94256 C57BL/6J ±  kb
transcript OTTMUST00000053628 VEGA | MGI Sequence Detail 6102 Not Applicable  
polypeptide OTTMUSP00000025509 VEGA | MGI Sequence Detail 1425 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    355 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004704 B-cell CLL/lymphoma 9 protein
  • InterPro Domains
    IPR015668 B Cell Lymphoma 9
    IPR024670 B-cell lymphoma 9, beta-catenin binding domain
Molecular
Reagents
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  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
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MGI:1919744, MGI:2441728, MGI:2684976
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:213694 Cantu C, et al., Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development. Genes Dev. 2014 Sep 1;28(17):1879-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory