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Agl
Gene Detail
 Symbol
Name
ID
Agl
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
MGI:1924809
Synonyms 1110061O17Rik, 9430004C13Rik, 9630046L06Rik
Feature Type protein coding gene
Genetic Map
Chromosome 3
50.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:116743051-116808129 bp, - strand
From VEGA annotation of GRCm38

  65079 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:536  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Agl

Human
homologs
Human Homolog AGL, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
NCBI Gene ID 178
neXtProt AC  NX_P35573
Human Synonyms  GDE
Human Chr (Location)  1p21; chr1:99850077-99924023 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human AGL
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Agl interacts with 398 markers (Mir7-1, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process glycogen catabolic process, glycogen metabolic process, ...
Component cytoplasm, inclusion body, ...
Function 4-alpha-glucanotransferase activity, amylo-alpha-1,6-glucosidase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (146)    Tissues (104)    Images (26)
Theiler Stages: 11, 13, 22, 23, 28
Assay TypeResults
RNA in situ 140
RT-PCR 6
cDNA source data(61)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(64) Genomic(1) cDNA(61) Primer pair(1) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000034170 (Evidence)
Ensembl Gene ModelENSMUSG00000033400 (Evidence)
Entrez Gene77559 (Evidence)
UniGene237099
DFCITC1598518, TC1599515, TC1601129, TC1603766, TC1620994
DoTSDT.101212750, DT.486582, DT.91381603, DT.91425532, DT.94389851, DT.97370290
NIA Mouse Gene IndexU024576
Consensus CDS ProjectCCDS38613.1
International Mouse Knockout Project StatusAgl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034170 VEGA Gene Model | MGI Sequence Detail 65079 C57BL/6J ±  kb
transcript OTTMUST00000086645 VEGA | MGI Sequence Detail 6434 Not Applicable 
polypeptide OTTMUSP00000046917 VEGA | MGI Sequence Detail 1532 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(5) UniProt(6)
Polymorphisms SNPs within 2kb(507 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010401 Amylo-alpha-1,6-glucosidase
InterPro IPR006421 Glycogen debranching enzyme, metazoa
InterPro IPR013781 Glycoside hydrolase, catalytic domain
InterPro IPR017853 Glycoside hydrolase, superfamily
InterPro IPR008928 Six-hairpin glycosidase-like
Protein Ontology PR:000003832 glycogen debranching enzyme
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)
Other
accession IDs
MGI:1916080, MGI:2139821, MGI:2140047, MGI:2442716

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory