Agl
Gene Detail

Symbol Name ID

Agl amylo-1,6-glucosidase, 4-alpha-glucanotransferase MGI:1924809

Synonyms

1110061O17Rik, 9430004C13Rik, 9630046L06Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 3

50.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:116743051-116808129 bp, - strand From VEGA annotation of GRCm38   65079 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:536  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Agl

Human homologs

Human Homolog		AGL, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
NCBI Gene ID		178
neXtProt AC		NX_P35573
Human Synonyms		GDE
Human Chr (Location)		1p21; chr1:100315640-100389579 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human AGL

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	glycogen catabolic process, glycogen metabolic process, ...
Component	cytoplasm, inclusion body, ...
Function	4-alpha-glucanotransferase activity, amylo-alpha-1,6-glucosidase activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (146)    Tissues (104)    Images (26)
Theiler Stages: 11, 13, 22, 23, 28

Assay Type	Results
RNA in situ	140
RT-PCR	6

cDNA source data(61)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(64) Genomic(1) cDNA(61) Primer pair(1) Other(1)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000034170 (Evidence)
Ensembl Gene Model	ENSMUSG00000033400 (Evidence)
Entrez Gene	77559 (Evidence)
UniGene	237099
DFCI	TC1598518, TC1599515, TC1601129, TC1603766, TC1620994
DoTS	DT.101212750, DT.486582, DT.91381603, DT.91425532, DT.94389851, DT.97370290
NIA Mouse Gene Index	U024576
Consensus CDS Project	CCDS38613.1
International Mouse Knockout Project Status	Agl

Sequences

Length	Strain/Species
genomic	OTTMUSG00000034170	VEGA Gene Model | MGI Sequence Detail	65079	C57BL/6J
transcript	OTTMUST00000086645	VEGA | MGI Sequence Detail	6434	Not Applicable
polypeptide	OTTMUSP00000046917	VEGA | MGI Sequence Detail	1532	Not Applicable

All sequences(67) RefSeq(3) UniProt(6)

Polymorphisms

SNPs(406 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR010401	Amylo-alpha-1,6-glucosidase
InterPro	IPR006421	Glycogen debranching enzyme, metazoa
InterPro	IPR013781	Glycoside hydrolase, catalytic domain
InterPro	IPR017853	Glycoside hydrolase, superfamily
InterPro	IPR008928	Six-hairpin glycosidase-like
Protein Ontology	PR:000003832	glycogen debranching enzyme

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)

Other accession IDs

MGI:1916080, MGI:2139821, MGI:2140047, MGI:2442716