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Dnhd1 Gene Detail
Summary
  • Symbol
    Dnhd1
  • Name
    dynein heavy chain domain 1
  • Synonyms
    8030491N06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924755
    NCBI Gene: 77505
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:105650827-105721799 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 55.93 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    250 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924755
protein coding gene Chr7:105650813-105721800 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032760
protein coding gene Chr7:108903663-108989677 (+)
A/J MGP_AJ_G0032740
protein coding gene Chr7:106050452-106136878 (+)
AKR/J MGP_AKRJ_G0032673
protein coding gene Chr7:108824605-108907093 (+)
BALB/cJ MGP_BALBcJ_G0032746
protein coding gene Chr7:105766980-105850539 (+)
C3H/HeJ MGP_C3HHeJ_G0032455
protein coding gene Chr7:108932260-109013491 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033251
protein coding gene Chr7:113263908-113349311 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030235
protein coding gene Chr7:108029211-108108811 (+)
CAST/EiJ MGP_CASTEiJ_G0031785
protein coding gene Chr7:100758938-100840361 (+)
CBA/J MGP_CBAJ_G0032429
protein coding gene Chr7:117027381-117123746 (+)
DBA/2J MGP_DBA2J_G0032582
protein coding gene Chr7:104320068-104401775 (+)
FVB/NJ MGP_FVBNJ_G0032535
protein coding gene Chr7:104129076-104209138 (+)
LP/J MGP_LPJ_G0032673
protein coding gene Chr7:110307223-110394271 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032567
protein coding gene Chr7:118613779-118701627 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033272
protein coding gene Chr7:107891826-107978552 (+)
PWK/PhJ MGP_PWKPhJ_G0031498
protein coding gene Chr7:97260310-97342498 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031347
protein coding gene Chr7:95002305-95088935 (+)
WSB/EiJ MGP_WSBEiJ_G0031902
protein coding gene Chr7:108534351-108615649 (+)



Homology
more
  • Human Ortholog
    DNHD1, dynein heavy chain domain 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DNHD1, dynein heavy chain domain 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C11orf47, CCDC35, DHCD1, DNHD1L
  • Links
    NCBI Gene ID: 144132
    neXtProt AC: NX_Q96M86
    UniProt: Q96M86

  • Chr Location
    11p15.4; chr11:6497296-6572025 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030882 Ensembl Gene Model | MGI Sequence Detail 70973 C57BL/6J ±  kb
transcript ENSMUST00000145988 Ensembl | MGI Sequence Detail 14536 Not Applicable  
polypeptide ENSMUSP00000121261 Ensembl | MGI Sequence Detail 4750 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR026983 Dynein heavy chain
    IPR041466 Dynein heavy chain, AAA 5 extension domain
    IPR024317 Dynein heavy chain, AAA module D4
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR041228 Dynein heavy chain, C-terminal domain
    IPR013602 Dynein heavy chain, domain-2
    IPR042228 Dynein heavy chain, domain 2, C-terminal
    IPR042222 Dynein heavy chain, domain 2, N-terminal
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region
    IPR004273 Dynein heavy chain region D6 P-loop domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 14
    Genomic 2
    cDNA 12

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 14
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory