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Stk31 Gene Detail
Summary
  • Symbol
    Stk31
  • Name
    serine threonine kinase 31
  • Synonyms
    C330007K24Rik, TDRD8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924735
    NCBI Gene: 77485
  • Gene Overview
    MyGene.info: STK31
Location & Maps
more
  • Sequence Map
    Chr6:49395604-49469501 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      73898 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 23.87 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    STK31, serine/threonine kinase 31
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STK31, serine/threonine kinase 31
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SGK396, TDRD8
  • Links
    NCBI Gene ID: 56164
    neXtProt AC: NX_Q9BXU1

  • Chr Location
    7p15.3; chr7:23710167-23832513 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 12677
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: STK31
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 3 alleles in 5 genetic backgrounds
    7 phenotype references
Mice homozygous for a null mutation display normal embryonic development and spermatogenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036462 VEGA Gene Model | MGI Sequence Detail 73898 C57BL/6J ±  kb
transcript OTTMUST00000093444 VEGA | MGI Sequence Detail 3237 Not Applicable  
polypeptide OTTMUSP00000051818 VEGA | MGI Sequence Detail 1018 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    274 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:225272 Zhou J, et al., Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L. Hum Mol Genet. 2015 Sep 11;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory