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Sec24a Gene Detail
Summary
  • Symbol
    Sec24a
  • Name
    Sec24 related gene family, member A (S. cerevisiae)
  • Synonyms
    9430090N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924621
    NCBI Gene: 77371
Location & Maps
more
  • Sequence Map
    Chr11:51692264-51763634 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      71371 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SEC24A, SEC24 homolog A, COPII coat complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC24A, SEC24 homolog A, COPII coat complex component
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 10802
    neXtProt AC: NX_O95486

  • Chr Location
    5q31.1; chr5:134648785-134727911 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    39
  • Chemically induced (other)
    1
  • Gene trapped
    36
  • Targeted
    2
  • Genomic Mutations
    1 involving Sec24a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005603 VEGA Gene Model | MGI Sequence Detail 71371 C57BL/6J ±  kb
transcript OTTMUST00000012466 VEGA | MGI Sequence Detail 6581 Not Applicable  
polypeptide OTTMUSP00000005765 VEGA | MGI Sequence Detail 1090 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    209 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 57
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2144209
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:213427 Adissu HA, et al., Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech. 2014 May;7(5):515-24

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory