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Sec24a
Gene Detail
 Symbol
Name
ID
Sec24a
Sec24 related gene family, member A (S. cerevisiae)
MGI:1924621
Synonyms 9430090N21Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
31.28 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:51692264-51763634 bp, - strand
From VEGA annotation of GRCm38

  71371 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:70131  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: vesicle coat complex COPII, subunit SEC24
Gene Tree: Sec24a

Human
homologs
Human Homolog SEC24A, SEC24 family member A
NCBI Gene ID 10802
neXtProt AC  NX_O95486
Human Chr (Location)  5q31.1; chr5:134648785-134727911 (+)  GRCh38
Alleles
and
phenotypes
All alleles(38) : Gene trapped(36) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process ER to Golgi vesicle-mediated transport, intracellular protein transport, ...
Component COPII vesicle coat, cytoplasm, ...
Function zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(57)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(57) cDNA(57)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000005603 (Evidence)
Ensembl Gene ModelENSMUSG00000036391 (Evidence)
Entrez Gene77371 (Evidence)
UniGene33878
DFCITC1581548, TC1586961, TC1602419, TC1612592, TC1665760, TC1679329
DoTSDT.110512117, DT.87047916, DT.87055065, DT.91351011, DT.91381226
NIA Mouse Gene IndexU032744
Consensus CDS ProjectCCDS24660.2, CCDS70181.1
International Mouse Knockout Project StatusSec24a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005603 VEGA Gene Model | MGI Sequence Detail 71371 C57BL/6J ±  kb
transcript OTTMUST00000012466 VEGA | MGI Sequence Detail 6581 Not Applicable 
polypeptide OTTMUSP00000005765 VEGA | MGI Sequence Detail 1090 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(7) UniProt(6)
Polymorphisms SNPs within 2kb(209 from dbSNP Build 137)    SNPs within 2kb including multiple locations(211)
Protein-related
information
ResourceIDDescription
InterPro IPR007123 Gelsolin domain
InterPro IPR012990 Sec23/Sec24 beta-sandwich
InterPro IPR006900 Sec23/Sec24, helical domain
InterPro IPR006896 Sec23/Sec24, trunk domain
InterPro IPR002035 von Willebrand factor, type A
InterPro IPR006895 Zinc finger, Sec23/Sec24-type
Protein Ontology PR:000014589 protein transport protein Sec24A
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:198477 Chen XW, et al., SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife. 2013;2:e00444
All references(38)
Other
accession IDs
MGI:2144209

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory