Sec24a
Gene Detail

Symbol

Name
ID

Sec24a
Sec24 related gene family, member A (S. cerevisiae)
MGI:1924621

Synonyms

9430090N21Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 11
31.28 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:51692264-51763634 bp, - strand From VEGA annotation of GRCm38   71371 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:70131  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: vesicle coat complex COPII, subunit SEC24
Gene Tree: Sec24a

Human
homologs

Human Homolog		SEC24A, SEC24 family member A
NCBI Gene ID		10802
neXtProt AC		NX_O95486
Human Chr (Location)		5q31.1; chr5:134648785-134727911 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(38) : Gene trapped(36) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Sec24a interacts with 371 markers (Mir7-1, Mir7-2, Mir7b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (14 annotations)

Process	ER to Golgi vesicle-mediated transport, intracellular protein transport, ...
Component	COPII vesicle coat, cytoplasm, ...
Function	zinc ion binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)

cDNA source data(57)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(57) cDNA(57)
Microarray probesets(2)

Other database
links

VEGA Gene Model	OTTMUSG00000005603 (Evidence)
Ensembl Gene Model	ENSMUSG00000036391 (Evidence)
Entrez Gene	77371 (Evidence)
UniGene	33878
DFCI	TC1679329, TC1612592, TC1665760, TC1602419, TC1586961, TC1581548
DoTS	DT.87055065, DT.87047916, DT.91351011, DT.91381226, DT.110512117
NIA Mouse Gene Index	U032744
Consensus CDS Project	CCDS24660.2, CCDS70181.1
International Mouse Knockout Project Status	Sec24a

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005603	VEGA Gene Model | MGI Sequence Detail	71371	C57BL/6J
transcript	OTTMUST00000012466	VEGA | MGI Sequence Detail	6581	Not Applicable
polypeptide	OTTMUSP00000005765	VEGA | MGI Sequence Detail	1090	Not Applicable

All sequences(71) RefSeq(7) UniProt(11)

Polymorphisms

SNPs within 2kb(209 from dbSNP Build 137)    SNPs within 2kb including multiple locations(211)

Protein-related
information

Resource	ID	Description
InterPro	IPR007123	Gelsolin domain
InterPro	IPR012990	Sec23/Sec24 beta-sandwich
InterPro	IPR006900	Sec23/Sec24, helical domain
InterPro	IPR006896	Sec23/Sec24, trunk domain
InterPro	IPR002035	von Willebrand factor, type A
InterPro	IPR006895	Zinc finger, Sec23/Sec24-type
Protein Ontology	PR:000014589	protein transport protein Sec24A

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:213427 Adissu HA, et al., Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech. 2014 May;7(5):515-24
All references(39)

Other
accession IDs

MGI:2144209