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Rspo4
Gene Detail
Symbol

Name
ID
Rspo4
R-spondin family, member 4
MGI:1924467
Synonyms
A930029K19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:151842927-151874668 bp, + strand
From VEGA annotation of GRCm38

  31742 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:65290  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: RSPO4
Gene Tree: Rspo4

Human
homologs
RSPO4, R-spondin 4
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 343637
neXtProt AC: NX_Q2I0M5

Human Synonyms: C20orf182, CRISTIN4

Human Chr (Location): 20p13; chr20:958452-1002284 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RSPO4

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Interactions
Rspo4 interacts with 180 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (14 records)
Data Summary: Results (224)    Tissues (213)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 220
RT-PCR 4
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(11) Primer pair(2) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000015809 (Evidence)
Ensembl Gene Model ENSMUSG00000032852 (Evidence)
Entrez Gene 228770 (Evidence)
UniGene 159868
DFCI TC1635801, TC1591529
DoTS DT.101720829
NIA Mouse Gene Index U002630
Consensus CDS Project CCDS38272.1
International Mouse Phenotyping Consortium Status Rspo4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015809 VEGA Gene Model | MGI Sequence Detail 31742 C57BL/6J ±  kb
transcript OTTMUST00000037592 VEGA | MGI Sequence Detail 2371 Not Applicable 
polypeptide OTTMUSP00000016847 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(296 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006212 Furin-like repeat
InterPro IPR009030 Insulin-like growth factor binding protein, N-terminal
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000014333 R-spondin-4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:210988 Kawasaki M, et al., R-spondins/Lgrs expression in tooth development. Dev Dyn. 2014 Jun;243(6):844-51
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory