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Rspo4
Gene Detail
 Symbol
Name
ID
Rspo4
R-spondin family, member 4
MGI:1924467
Synonyms A930029K19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:151842927-151874668 bp, + strand
From VEGA annotation of GRCm38

  31742 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:65290  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rspo4

Human
homologs
Human Homolog RSPO4, R-spondin 4
NCBI Gene ID 343637
neXtProt AC  NX_Q2I0M5
Human Synonyms  C20orf182, CRISTIN4
Human Chr (Location)  20p13; chr20:958452-1002284 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human RSPO4
Alleles
and
phenotypes
All alleles(4) : Targeted(4)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process response to stimulus, Wnt signaling pathway
Component extracellular region
Function heparin binding
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (224)    Tissues (213)    Images (23)
Theiler Stages: 10, 11, 13, 15, 17, 18, 20, 22, 23, 25, 28
Assay TypeResults
RNA in situ 220
RT-PCR 4
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(14) cDNA(11) Primer pair(2) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000015809 (Evidence)
Ensembl Gene ModelENSMUSG00000032852 (Evidence)
Entrez Gene228770 (Evidence)
UniGene159868
DFCITC1591529, TC1635801
DoTSDT.101720829
NIA Mouse Gene IndexU002630
Consensus CDS ProjectCCDS38272.1
International Mouse Knockout Project StatusRspo4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015809 VEGA Gene Model | MGI Sequence Detail 31742 C57BL/6J ±  kb
transcript OTTMUST00000037592 VEGA | MGI Sequence Detail 2371 Not Applicable 
polypeptide OTTMUSP00000016847 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(296 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006212 Furin-like repeat
InterPro IPR009030 Insulin-like growth factor binding protein, N-terminal
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000014333 R-spondin-4
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202907 Grigoryan T, et al., Wnt/Rspondin/beta-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18174-9
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory